DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and Hil

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_611493.2	Gene:	Hil / 37328	FlyBaseID:	FBgn0050147	Length:	818	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	62/278 - (22%)
Similarity:	93/278 - (33%)	Gaps:	108/278 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 CPRCGIYVYAAEQM--LARGKGYHRRCFKCVQCN-----KTLDSTLHCDGPDKDIYCRGCYAQKF 165
            |.||...||..:::  |.....:|..|||||.|.     ||..:..| ...||::|| ..:..|.
  Fly    11 CLRCSETVYQVDRVGPLKDFTFFHSGCFKCVHCGTKLTLKTYFNNQH-KQDDKEVYC-SSHVPKS 73

  Fly   166 GARGYGHIGISSLGLMSDIRDSEWQSDMAPKASIINVEQIQAPIGE--GCPRCGGVVFAAEQVLS 228
            |.   ||:..:|:|:.        |:..||:.:....|||:....|  |.|..|.
  Fly    74 GP---GHLDQTSVGIR--------QALNAPRTNKFVNEQIRGTRSEVDGGPLGGS---------- 117

  Fly   229 KGRSWHRKCFKCRDCTKTLDSIIACDGPDNEVYCKTCYGKKWGPHGYGFACGSSFLQTDGITEEN 293
                        |..|                           |:|||....||..|.|
  Fly   118 ------------RQST---------------------------PNGYGSREISSPSQND------ 137

  Fly   294 LASERPFVAPDTTSIMAPDGEGCPRCGGAVFAAELQLSKGKMYHRKCFNCARCTRPLDSVLACD- 357
              |:..:...|.:::         ....|:...|:|         |.:|.|| .:|:|..||.:
  Fly   138 --SDYKYGRFDASAL---------HIAHALKQTEIQ---------KAYNKAR-EKPIDFYLAREE 181

  Fly   358 ---------GPDDNIYCK 366
                     ..:|::|.|
  Fly   182 QAHLEMKHRKEEDDLYRK 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788
		LIM_CRP_like	108..161	CDD:188712	20/59 (34%)
		LIM_CRP_like	213..266	CDD:188712	4/52 (8%)
		LIM	316..369	CDD:413332	14/61 (23%)
		LIM_CRP_like	412..465	CDD:188712
Hil	NP_611493.2	LIM_Ltd-1	11..70	CDD:188827	20/60 (33%)
		BAR	<147..>265	CDD:299863	14/72 (19%)
		TGc	418..486	CDD:214673
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900