DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and Csrp1

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_058844.1	Gene:	Csrp1 / 29276	RGDID:	62053	Length:	193	Species:	Rattus norvegicus

Alignment Length:	174	Identity:	83/174 - (47%)
Similarity:	108/174 - (62%)	Gaps:	13/174 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFCKNCHGRKYGPKGYGF 74
            ||..|.|:||.|||....|..|||:||.|.:|.|.||||....|.:|::||:|:|:||||||||:
  Rat     9 KCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKSCYGKKYGPKGYGY 73

  Fly    75 GGGAGCLSTDTGAHL--NREFVPPKIPPKAPDG------LG----CPRCGIYVYAAEQMLARGKG 127
            |.|||.||.|.|..|  ..|..|...|...|:.      :|    ||||...|||||:::..||.
  Rat    74 GQGAGTLSMDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCPRCSQAVYAAEKVIGAGKS 138

  Fly   128 YHRRCFKCVQCNKTLDSTLHCDGPDKDIYCRGCYAQKFGARGYG 171
            :|:.||:|.:|.|.|:||...| .|.:|||:||||:.||.:|:|
  Rat   139 WHKSCFRCAKCGKGLESTTLAD-KDGEIYCKGCYAKNFGPKGFG 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	26/52 (50%)
		LIM_CRP_like	108..161	CDD:188712	26/52 (50%)
		LIM_CRP_like	213..266	CDD:188712
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
Csrp1	NP_058844.1	LIM1_CRP1	8..63	CDD:188863	27/53 (51%)
		Nuclear localization signal. /evidence=ECO:0000255	64..69		3/4 (75%)
		LIM2_CRP	119..172	CDD:188787	27/53 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335997
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750