DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp60A and Csrp2

DIOPT Version :9

Sequence 1:	NP_001137750.1	Gene:	Mlp60A / 37853	FlyBaseID:	FBgn0259209	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_031818.3	Gene:	Csrp2 / 13008	MGIID:	1202907	Length:	193	Species:	Mus musculus

Alignment Length:	175	Identity:	79/175 - (45%)
Similarity:	110/175 - (62%)	Gaps:	13/175 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KCPACGKSVYAAEERVAGGYKFHKTCFKCSMCNKALDSTNCTEHEKELFCKNCHGRKYGPKGYGF 74
            ||.|||::||.|||....|..||:.||.|.:|.|.||||....|::|::||:|:|:||||||||:
Mouse     9 KCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPKGYGY 73

  Fly    75 GGGAGCLSTDTGAHL--NREFVPPKIPPKAPD----------GLGCPRCGIYVYAAEQMLARGKG 127
            |.|||.|:.|.|..|  ..|...|..|...|:          ...|.|||..|||||:::..||.
Mouse    74 GQGAGTLNMDRGERLGIKPESAQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKP 138

  Fly   128 YHRRCFKCVQCNKTLDSTLHCDGPDKDIYCRGCYAQKFGARGYGH 172
            :|:.||:|.:|.|:|:||...: .:.:|||:||||:.||.:|:|:
Mouse   139 WHKNCFRCAKCGKSLESTTLTE-KEGEIYCKGCYAKNFGPKGFGY 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp60A	NP_001137750.1	LIM1_MLP84B_like	10..63	CDD:188788	26/52 (50%)
		LIM_CRP_like	108..161	CDD:188712	24/52 (46%)
		LIM_CRP_like	213..266	CDD:188712
		LIM	316..369	CDD:413332
		LIM_CRP_like	412..465	CDD:188712
Csrp2	NP_031818.3	LIM1_CRP2	9..63	CDD:188864	27/53 (51%)
		Nuclear localization signal. /evidence=ECO:0000255	64..69		3/4 (75%)
		LIM2_CRP2	119..172	CDD:188871	25/53 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832344
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750