Protein Alignment Gpat4 and AUP1

DIOPT Version :10

• Sequence 1: NP_001286818.1
• Gene: Gpat4 / 37852
• FlyBaseID: FBgn0034971
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_853553.1
• Gene: AUP1 / 550
• HGNCID: 891
• Length: 410
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 64/271 - (23%)
• Similarity: 111/271 - (40%)
• Gaps: 61/271 - (22%)

  Fly   244 YKPTVSGFCVANHTSPLDVAILSTDCTYSLVVWLTVCTAAVGYLKDGPFKRDLVHKVLGMC--FG 306
            |.|.  |||           :|.......:.|:|..|.     |.|...:|.:|..   ||  .|
Human    31 YAPV--GFC-----------LLVLRLFLGIHVFLVSCA-----LPDSVLRRFVVRT---MCAVLG 74

  Fly   307 VLSSAISAVITYHNEDNRPSSGICVANHTSPIDVLVLMCDSTYSLIGQRHGGFLGVLQRALARAS 371
            :::....:.:..|      |..:.::||.:|.|         ::::     ..|......|..:.
Human    75 LVARQEDSGLRDH------SVRVLISNHVTPFD---------HNIV-----NLLTTCSTPLLNSP 119

  Fly   372 P-HIWFERG--EAKDRHLVAERLKQHVSDPNNP--PILIFPEGTCIN-NTSVMQFKKGSFEVGGV 430
            | .:.:.||  |...|..:.|.||:..:....|  |:|:|||....| ...:::|....|.:..|
Human   120 PSFVCWSRGFMEMNGRGELVESLKRFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDV 184

  Fly   431 IYPVAIK-----YDPRFGDAFWNSAKYSMMQYLYMMMTSWAIVCDVWYLPPMYRQEGESAIDFAN 490
            :.|:.::     ......||.|.|   .::..|::..|    |..|.:|.|::||.||:..:||.
Human   185 VQPLTLQVQRPLVSVTVSDASWVS---ELLWSLFVPFT----VYQVRWLRPVHRQLGEANEEFAL 242

  Fly   491 RVKSVIAKQGG 501
            ||:.::||:.|
Human   243 RVQQLVAKELG 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpat4	NP_001286818.1	LPLAT_LPCAT1-like	307..513	CDD:153253	48/206 (23%)
AUP1	NP_853553.1	LPLAT	66..264	CDD:473073	52/218 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..295
		CUE_AUP1	296..340	CDD:270603
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	350..369