DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment yki and UBE3C

DIOPT Version :9

Sequence 1:NP_001350857.1 Gene:yki / 37851 FlyBaseID:FBgn0034970 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_055486.2 Gene:UBE3C / 9690 HGNCID:16803 Length:1083 Species:Homo sapiens


Alignment Length:129 Identity:32/129 - (24%)
Similarity:50/129 - (38%) Gaps:41/129 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 IILCSF--------RLYTI--SAFYMLTTMSASS---------NTNSLIE------KEIDDEDML 48
            ||:.||        :.|:|  |||....|:|.|.         |...|:.      |:.:|...|
Human    50 IIIQSFIRGYRDRKQQYSIQRSAFDRCATLSQSGGAFPIANGPNLTLLVRQLLFFYKQNEDSKRL 114

  Fly    49 -----SPIKSNNLVVRVNQDTDDNLQALFD----------SVLNPGDAKRPLQLPLRMRKLPNS 97
                 :.||.::|.|: ..|..:.|..||.          .:.|..|....:.||:||.::.:|
Human   115 IWLYQNLIKHSSLFVK-QLDGSERLTCLFQIKRLMSLCCRLLQNCNDDSLNVALPMRMLEVFSS 177

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ykiNP_001350857.1 HUL4 <261..>404 CDD:227354
WW 266..295 CDD:395320
WW 335..364 CDD:395320
UBE3CNP_055486.2 Cis-determinant of acceptor ubiquitin-binding 1..60 4/9 (44%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..40
IQ 47..64 CDD:197470 4/13 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 355..385
HECTc 725..1081 CDD:238033
HECTc 747..1080 CDD:214523
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.