DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment yki and Herc6

DIOPT Version :9

Sequence 1:NP_001350857.1 Gene:yki / 37851 FlyBaseID:FBgn0034970 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_080268.1 Gene:Herc6 / 67138 MGIID:1914388 Length:1003 Species:Mus musculus


Alignment Length:308 Identity:62/308 - (20%)
Similarity:104/308 - (33%) Gaps:73/308 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 YDAGSQSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSPQHSRLAIHH-----SRARSSPASLQQ 175
            :.|||:..:.||....|...|.....:|.|..:|:.....|| ||:..     |..|:|...|..
Mouse    98 WGAGSEGQLGIGEFKEISFMPTKIKALAGIKIIQVSCGHYHS-LALSEDGHVFSWGRNSEGQLGL 161

  Fly   176 NYNVRARSDAAAANNPNANPSSQQQPAGPTFPENSAQEFPSGAPASSAIDLDAMN----TCMSQD 236
            ..|.|:::......:....|.:|               ..:|...|.|:.|...:    :..|..
Mouse   162 GKNSRSQAIPQKVKSLEGIPLAQ---------------VAAGGTHSFALSLTGTSFGWGSNRSGQ 211

  Fly   237 IPMSMQTVHKKQRSYDVISPIQLNRQLGALPP--------GWEQAK--TNDGQIYYLNHTTKSTQ 291
            :.:|...|  |::.|...|       :|||..        |:|...  |.:||::.....:....
Mouse   212 LALSGNKV--KEQIYKPHS-------IGALKNLSVIYISCGYEHTAVLTEEGQVFTFGGNSSGQL 267

  Fly   292 WEDPRIQYRQQQQIL-MAERIKQNDVLQ----TTKQTTTSTIANNLGPLPDGWEQAVTESGDLYF 351
            ...||...|..|.|. :..|:.|.:...    ....||...::...||                 
Mouse   268 QPSPRSGQRGPQLIEGIGGRVSQIECASYHTIAYVYTTGQVVSLGRGP----------------- 315

  Fly   352 INHIDRTTSWNDPRMQSGLSVLDCPDNLVSSLQIEDNLCSNLFNDAQA 399
             :|....|....|...|.::.|...::|| .::::|     :|..|.|
Mouse   316 -SHTSNPTHQEAPAENSDITCLLAAEDLV-DIEVKD-----IFAGAHA 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ykiNP_001350857.1 HUL4 <261..>404 CDD:227354 30/154 (19%)
WW 266..295 CDD:395320 6/38 (16%)
WW 335..364 CDD:395320 2/28 (7%)
Herc6NP_080268.1 RCC1 1 40..91
RCC1 40..89 CDD:278826
RCC1 2 92..144 14/46 (30%)
RCC1 92..142 CDD:278826 13/44 (30%)
RCC1 145..195 CDD:278826 10/64 (16%)
RCC1 3 146..197 11/65 (17%)
RCC1_2 183..211 CDD:290274 6/42 (14%)
RCC1 4 199..252 11/61 (18%)
RCC1_2 237..266 CDD:290274 5/28 (18%)
RCC1 5 253..303 9/49 (18%)
RCC1 253..300 CDD:278826 9/46 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 261..281 4/19 (21%)
chaperonin_like <570..>652 CDD:295468
HECTc 658..999 CDD:238033
HECTc 682..999 CDD:214523
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.