DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yki and plekha5

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_021330752.1	Gene:	plekha5 / 567300	ZFINID:	ZDB-GENE-041210-25	Length:	1398	Species:	Danio rerio

Alignment Length:	149	Identity:	37/149 - (24%)
Similarity:	61/149 - (40%)	Gaps:	35/149 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 LGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTKQTTTST 327
            |..||..|....|.||:::::|...|||.|..|               :....|:...::|.
Zfish    10 LSCLPSSWSYGVTRDGRVFFINEEAKSTTWLHP---------------VTGEAVITGHRKTP--- 56

  Fly   328 IANNLGPLPDGWEQAVTESGDLYFINHIDRTTSWNDPRMQSGLSVLDCPDNLVSSLQIEDNL-CS 391
                  .||.|||:..|..|...||||.:|..:...|     :|.:...||.:  ..:.::| |.
Zfish    57 ------DLPTGWEEGYTFEGARCFINHNERKVTCKHP-----VSGVPSQDNCI--FVVNEHLNCG 108

  Fly   392 NLFNDAQAIVNPPSSHKPD 410
            ||   ...:::.|::..|:
Zfish   109 NL---VHPVLSRPATKAPE 124

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	35/141 (25%)
		WW	266..295	CDD:395320	11/28 (39%)
		WW	335..364	CDD:395320	12/28 (43%)
plekha5	XP_021330752.1	WW	13..42	CDD:306827	11/28 (39%)
		WW	58..87	CDD:306827	12/28 (43%)
		PH_PEPP1_2_3	177..280	CDD:270068
		SMC_N	822..>983	CDD:330553
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900