DRSC/TRiP Functional Genomics Resources

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Protein Alignment yki and wwp2

DIOPT Version :9

Sequence 1:NP_001350857.1 Gene:yki / 37851 FlyBaseID:FBgn0034970 Length:418 Species:Drosophila melanogaster
Sequence 2:XP_005163228.1 Gene:wwp2 / 564527 ZFINID:ZDB-GENE-000607-82 Length:867 Species:Danio rerio


Alignment Length:356 Identity:96/356 - (26%)
Similarity:142/356 - (39%) Gaps:103/356 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    94 LPNSFFTPPAPSHS--RANSADSTYD---AGSQSSINIGNKASIVQQPDGQSPIAAIP---QLQI 150
            |.::..|.||||..  .:|..|.|..   |...:|....:..|..|..|      |:|   :.:|
Zfish   248 LESAHLTCPAPSSPSLSSNPPDGTVPPPAAEPPASTEQSDTTSDTQNTD------ALPAGWEQRI 306

  Fly   151 QPSPQHSRL--AIHHSRA----RSSPASLQQNYNVRARSDAAAANNPNANPSSQQQPAGPTFPEN 209
            .|   |.|:  ..|:::.    |..|...::..:.|.|....   :.|...::.|:|.       
Zfish   307 LP---HGRVYYVDHNTKTTTWERPLPPGWEKRVDQRGRFYYV---DHNTRTTTWQRPT------- 358

  Fly   210 SAQEFPSGAPASSAIDLDAMNTCMSQDIPMSMQTVHKKQRSYDVISPIQLNRQLGALPPGWEQAK 274
                      |.|..:.:...:..|| :..:||..:::. .|.....:..|..|||||||||:.:
Zfish   359 ----------AESVRNYEQWQSQRSQ-LQGAMQQFNQRY-LYQPSGAVVENDPLGALPPGWEKRQ 411

  Fly   275 TNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIANNLGPLPDGW 339
            .| |::||:||.|::|||||||.|...|:.                             |||.||
Zfish   412 DN-GRVYYVNHNTRTTQWEDPRTQGMIQEP-----------------------------PLPPGW 446

  Fly   340 EQAVTESGDLYFINHIDRTTSWNDPR--MQSGL------SVLD-------------CPDN-LVSS 382
            |...|..|..||::|..|||::.|||  .:||.      ...|             |..| |.|.
Zfish   447 EMKYTAEGVRYFVDHNSRTTTFKDPRPGFESGSRQGGSPGAYDRSFRWKYHQFRFLCHSNALPSH 511

  Fly   383 LQIEDNLCSNLFNDA-QAIVNPPSSHKPDDL 412
            ::|..:. ..||.|: |.|:|    .||.||
Zfish   512 VKISVSR-QTLFEDSFQQIMN----MKPYDL 537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ykiNP_001350857.1 HUL4 <261..>404 CDD:227354 56/165 (34%)
WW 266..295 CDD:395320 17/28 (61%)
WW 335..364 CDD:395320 13/28 (46%)
wwp2XP_005163228.1 C2_E3_ubiquitin_ligase 17..145 CDD:175988
WW 298..327 CDD:197736 6/31 (19%)
WW 328..357 CDD:278809 5/31 (16%)
WW 403..431 CDD:278809 17/28 (61%)
WW 441..473 CDD:197736 16/31 (52%)
HECTc 513..865 CDD:238033 11/30 (37%)
HECTc 536..864 CDD:214523 2/2 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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