DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yki and magi2a

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001314782.1	Gene:	magi2a / 564112	ZFINID:	ZDB-GENE-050810-4	Length:	1503	Species:	Danio rerio

Alignment Length:	222	Identity:	64/222 - (28%)
Similarity:	93/222 - (41%)	Gaps:	60/222 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 PNANPSSQ-----------QQPAGPTFPENSAQEFP----SG---APASSAID---LDAMNTCMS 234
            |.|.|:||           .:.||...||...:|.|    :|   .|.||..:   .||... |:
Zfish   209 PGATPTSQGKRRRNKSVSNMEKAGIEPPEEEEEERPVINGNGVAITPESSEHEDKSTDASGE-MA 272

  Fly   235 QDIPMSMQTVHKKQRSYDVISPIQ--LNRQLGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRI 297
            ...|....|...|:.:....||.:  .|.:||.||..||.|.|..|::|:::|.||:|.|.|||:
Zfish   273 TTCPSETSTDAPKEDTEPPKSPPKPDENDELGPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRL 337

  Fly   298 QYRQQQQILMAERIKQNDVLQTTKQTTTSTIANNLGPLPDGWEQAVTESGDLYFINHIDRTTSWN 362
            ..:.:.    .|..|:|:                   ||.|||:........|:::||:|.|.:.
Zfish   338 AKKAKP----PEECKENE-------------------LPYGWEKIDDPIYGTYYVDHINRRTQFE 379

  Fly   363 DP------------RMQS-GLSVLDCP 376
            :|            :||| |||.|..|
Zfish   380 NPVLEAKRRLQHQQQMQSQGLSSLPLP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	40/129 (31%)
		WW	266..295	CDD:395320	13/28 (46%)
		WW	335..364	CDD:395320	10/28 (36%)
magi2a	NP_001314782.1	PDZ_signaling	25..100	CDD:238492
		NK	122..286	CDD:302627	20/77 (26%)
		WW	307..337	CDD:238122	14/29 (48%)
		WW	352..381	CDD:278809	10/28 (36%)
		PDZ	431..511	CDD:214570
		PDZ	595..676	CDD:214570
		PDZ	762..856	CDD:214570
		PDZ_signaling	920..1007	CDD:238492
		PDZ_signaling	1182..1262	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900