DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment yki and hectd2

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_009304826.1	Gene:	hectd2 / 562999	ZFINID:	ZDB-GENE-100405-3	Length:	756	Species:	Danio rerio

Alignment Length:	165	Identity:	38/165 - (23%)
Similarity:	54/165 - (32%)	Gaps:	56/165 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 QQQPAGPTFPENSAQEFPSGAPASSAIDLDAMNTCMSQDIPMSMQTVHKKQR-SYDVISPIQLN- 260
            |....||..|      |||.....|.::                   ||::. |:...||:.|.
Zfish    27 QNLERGPKLP------FPSYGSFISTLN-------------------HKRESGSHSFSSPLFLPA 66

  Fly   261 -RQLGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTKQTT 324
             :|:..|||           ||           .|.|.::|....:|..| :|...|.:......
Zfish    67 VKQVRELPP-----------IY-----------PDVRQKHRISIDVLPPE-VKARFVSEPIIPIR 108

  Fly   325 TSTIANNLGPLPDGWEQAVTESGDLYFINHIDRTT 359
            |.|...    ..|..|:| |.|||...::....||
Zfish   109 TKTAKE----FQDDVERA-TISGDWKHVHDFYLTT 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	24/99 (24%)
		WW	266..295	CDD:395320	5/28 (18%)
		WW	335..364	CDD:395320	9/25 (36%)
hectd2	XP_009304826.1	HECTc	397..754	CDD:238033
hectd2	XP_009304826.1	HECTc	420..753	CDD:214523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900