DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment yki and ASCC1

DIOPT Version :9

Sequence 1:NP_001350857.1 Gene:yki / 37851 FlyBaseID:FBgn0034970 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_001185728.1 Gene:ASCC1 / 51008 HGNCID:24268 Length:400 Species:Homo sapiens


Alignment Length:165 Identity:41/165 - (24%)
Similarity:63/165 - (38%) Gaps:30/165 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 IEKEIDDEDMLSPIKSNNLVVRVN-QDTDDNLQALFDSVLNPGDAKRPLQLPLRMRKL----PNS 97
            ||...||..|:     :.|..:|: :|..:.||.|.|.||....|...:.......||    .|:
Human   252 IEYMNDDPGMV-----DVLYAKVHMKDGSNRLQELVDRVLERFQASGLIVKEWNSVKLHATVMNT 311

  Fly    98 FFTPPAPSHSRAN--SADSTYDAGSQSSINIGNKASIVQQPDGQS---PIAAIPQLQIQPS-PQH 156
            .|.....:..|.|  :|:..|....:.|.            ||::   ..|.:|:|:...: ..|
Human   312 LFRKDPNAEGRYNLYTAEGKYIFKERESF------------DGRNILKSFALLPRLEYNDAISAH 364

  Fly   157 SRLAIHHSRARSSPASLQQNYNVRARSDAAAANNP 191
            ..|.:..|  ..||||..|...:...|||.:.:.|
Human   365 CNLCLPGS--SDSPASASQVAGITGVSDAYSQSLP 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ykiNP_001350857.1 HUL4 <261..>404 CDD:227354
WW 266..295 CDD:395320
WW 335..364 CDD:395320
ASCC1NP_001185728.1 Required for interaction with ASCC3. /evidence=ECO:0000269|PubMed:29997253 1..53
vigilin_like_KH 99..148 CDD:239087
PLN00108 157..370 CDD:177724 31/134 (23%)
AKAP7_NLS 161..349 CDD:287446 26/113 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.