DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yki and Magi1

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_038964101.1	Gene:	Magi1 / 500261	RGDID:	1586025	Length:	1491	Species:	Rattus norvegicus

Alignment Length:	229	Identity:	53/229 - (23%)
Similarity:	92/229 - (40%)	Gaps:	59/229 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 AIH--HSRARSSPASLQQNYNVRARSDAAAANNPNANPSSQQQPAGPTFPENSAQEFPSGAPASS 222
            |:|  .|.::.|.....::||                   ..|.||....||..:|
  Rat   206 ALHSLQSGSKQSTPKRTKSYN-------------------DMQNAGIVHTENEEEE--------- 242

  Fly   223 AIDLDAMNTCMS-----QDIPMSMQT-------------VHKKQRSYDVISPIQLNRQLGALPPG 269
              |:..||:..:     ||.|...:.             :....:.:....|:.....||.||..
  Rat   243 --DVPEMNSSFTADSGDQDEPTLQEATLPPVNSSALAAPITDPSQKFPQYLPLSAEDNLGPLPEN 305

  Fly   270 WEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIANNLGP 334
            ||.|.|.:|::|:::|.||:|.|.|||...:||:.:...|..::.        ..|..:.:.| .
  Rat   306 WEMAYTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEEG--------VHTEELDSEL-E 361

  Fly   335 LPDGWEQAVTESGDLYFINHIDRTTSWNDPRMQS 368
            ||.|||:.......:|:::||:|.|.:.:|.:::
  Rat   362 LPAGWEKIEDPVYGVYYVDHINRKTQYENPVLEA 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	34/108 (31%)
		WW	266..295	CDD:395320	13/28 (46%)
		WW	335..364	CDD:395320	10/28 (36%)
Magi1	XP_038964101.1	NK	122..293	CDD:418433	18/116 (16%)
		WW	302..331	CDD:395320	13/28 (46%)
		WW	362..393	CDD:197736	11/30 (37%)
		PDZ	469..555	CDD:214570
		PDZ	640..723	CDD:214570
		MAGI_u5	724..806	CDD:406953
		PDZ_signaling	847..922	CDD:238492
		PDZ_signaling	996..1091	CDD:238492
		PDZ	1152..1234	CDD:214570
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900