DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yki and Herc3

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001102101.1	Gene:	Herc3 / 362377	RGDID:	1307803	Length:	1050	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	67/405 - (16%)
Similarity:	122/405 - (30%)	Gaps:	139/405 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 HSRANSADS---TYDAGSQSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSPQHS---------- 157
            |..|.:||.   |:...|...:.:|.:......|.....:..||..|:.....||
  Rat   148 HCLALAADGQFFTWGKNSHGQLGLGKEFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVF 212

  Fly   158 --------RLAIHHSRARSSPASLQQNYNVRARSDAAAANNPNANPSSQQQPAGPTFPENSAQEF 214
                    :|.:...:.|.||..::.   :|.:.....:       ..::..|..|   .|...|
  Rat   213 GWGMNNAGQLGLSDEKDRESPCHVKL---LRTQKVVYIS-------CGEEHTAVLT---KSGGVF 264

  Fly   215 PSGAPASSAIDLDAMNTCMSQDIPMSMQTVHKKQRSYDVISPIQLNRQLG--------------A 265
            ..||.:...:..|::|                     |.::|.::...:|              |
  Rat   265 TFGAGSCGQLGHDSVN---------------------DEVNPRRVLELMGSEVTQIACGRQHTLA 308

  Fly   266 LPPGWEQAKTNDGQIYYL----------NHTTK-------STQW---------EDPRIQYRQQQQ 304
            |.|       :.|.||..          .||..       ...|         ...|.:||..:|
  Rat   309 LVP-------SSGLIYAFGCGAKGQLGTGHTCNVKCPSPVKGHWAAHSGQLSARADRFKYRVVKQ 366

  Fly   305 ILMAERIKQNDVLQTTKQTTTSTI-------ANNLGPLPDG----WEQAVTESGDLYFINHIDRT 358
            |....  .|..||.:|.:.::..:       |:....:.|.    |.|.:||..:...:|.:.:.
  Rat   367 IFSGG--DQTFVLCSTYENSSPAVDFRTVNQAHYTNLINDETIAVWRQKLTEHNNANTVNGVVQI 429

  Fly   359 TS----WN--------DPRMQSGLSVLDCPDNLVSSLQI---------EDNLCSNLFNDAQAIVN 402
            .|    ||        |...::...:   |...::|.::         ...:...:.|..::.:.
  Rat   430 LSSAACWNGSFLEKKIDEHFKTSPKI---PGIDLNSTRVLFEKLMHSQHSMILEQILNSFESCLI 491

  Fly   403 PPSSHKPDDLEWYKI 417
            |..|..|.|:|..:|
  Rat   492 PQLSSSPPDVEAMRI 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	33/214 (15%)
		WW	266..295	CDD:395320	8/54 (15%)
		WW	335..364	CDD:395320	9/44 (20%)
Herc3	NP_001102101.1	ATS1	2..331	CDD:227511	35/223 (16%)
		RCC1	313..377	CDD:395335	12/65 (18%)
		HECTc	702..1048	CDD:238033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900