DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yki and Hectd3

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_008762291.1	Gene:	Hectd3 / 313525	RGDID:	1309823	Length:	861	Species:	Rattus norvegicus

Alignment Length:	155	Identity:	32/155 - (20%)
Similarity:	59/155 - (38%)	Gaps:	39/155 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 TNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIAN--------- 330
            |.:..:..|..:...|.||....|.:...::.|    |:..:::....|..:|..|
  Rat   253 TEEFNVSCLTDSNADTYWESDGSQCQHWVRLTM----KKGTIVKKLLLTVDTTDDNFMPKRVVVY 313

  Fly   331 -----NLGPLPDGWEQAVTES--GDLYFINHIDRTTSWNDPRMQSGLSVLDCPDN---------- 378
                 ||..|.|   ..:.|:  ||:..:.  |.|.  :.|.::  :.:::|.|:
  Rat   314 GGEGDNLKKLSD---VNIDETLIGDVCVLE--DMTV--HLPVIE--IRIVECRDDGIDVRLRGVK 369

  Fly   379 LVSSLQIEDNLCSNLFNDAQAIVNP 403
            :.||.|.|..|.::||..|..:..|
  Rat   370 IKSSRQRELGLNADLFQPASLVRYP 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	32/155 (21%)
		WW	266..295	CDD:395320	5/19 (26%)
		WW	335..364	CDD:395320	7/30 (23%)
Hectd3	XP_008762291.1	APC10-HECTD3	238..371	CDD:176487	23/130 (18%)
Hectd3	XP_008762291.1	HECT	579..845	CDD:395507
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900