| Sequence 1: | NP_001350857.1 | Gene: | yki / 37851 | FlyBaseID: | FBgn0034970 | Length: | 418 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_056287.1 | Gene: | WWTR1 / 25937 | HGNCID: | 24042 | Length: | 400 | Species: | Homo sapiens |
| Alignment Length: | 398 | Identity: | 98/398 - (24%) |
|---|---|---|---|
| Similarity: | 134/398 - (33%) | Gaps: | 171/398 - (42%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 57 VVRVNQDTDDNLQALFDSVLNPGDAKRPLQLPLRMRK--LPNSFF-TPPAPSHSRANSADSTYDA 118
Fly 119 GSQSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSPQHSRLA--IHHSRARSSPASLQQNYNVRA 181
Fly 182 RSDAAAANNPNANPSSQQQPAGPTFPENSAQEFPSGAPASSAIDLDAMNTCMSQDIPMSMQTVHK 246
Fly 247 KQRSYDVISPIQLNRQLGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERI 311
Fly 312 KQNDVLQTTKQTTTSTIANNLGPLPDGWEQAVTESGDLYFINHIDR-------TTSWNDPRMQSG 369
Fly 370 LSVLDCPDNLVSSLQIEDN--------------------------LCSNLFNDA------QAIVN 402
Fly 403 PPSSHKPD 410 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| yki | NP_001350857.1 | HUL4 | <261..>404 | CDD:227354 | 39/181 (22%) |
| WW | 266..295 | CDD:459800 | 16/28 (57%) | ||
| WW | 335..364 | CDD:459800 | 5/35 (14%) | ||
| WWTR1 | NP_056287.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 52..117 | 32/154 (21%) | |
| WW | 125..156 | CDD:197736 | 17/30 (57%) | ||
| Required for interaction with PALS1. /evidence=ECO:0000269|PubMed:21145499 | 222..400 | 15/67 (22%) | |||
| PDZ-binding | 394..400 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||