DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yki and herc-1

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_490834.1	Gene:	herc-1 / 171700	WormBaseID:	WBGene00021685	Length:	1019	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	31/152 - (20%)
Similarity:	51/152 - (33%)	Gaps:	33/152 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 HSRANSADSTYDAGSQSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSPQHSRLAIHHSRARSSP 170
            |:.|....:.|..|..||..:||                 .::..|.:|:.:....|   .....
Worm   306 HTIAICKGAPYPFGLNSSGQLGN-----------------GKIMTQSTPRKTDELDH---VTGVF 350

  Fly   171 ASLQQNYNVRARSDAAAANNPNANPSSQQQPAGPTFP----ENSAQEFPSGAPASSAIDLDAMNT 231
            |...|.:.|  ||......|....||...|     :|    ..|.::......|...:.|  :.:
Worm   351 AGYHQTFFV--RSSGTIEQNEIVGPSCPMQ-----YPIKLDHESLKKLLDEGDALEVMSL--IES 406

  Fly   232 CMSQDIPMSMQTVHKKQRSYDV 253
            ..|....|:|..::|.:|.|:|
Worm   407 VFSSLASMNMSFLYKDERRYNV 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354
		WW	266..295	CDD:395320
		WW	335..364	CDD:395320
herc-1	NP_490834.1	ATS1	2..359	CDD:227511	13/72 (18%)
herc-1	NP_490834.1	HECTc	667..1016	CDD:238033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900