Protein Alignment yki and Nedd4

DIOPT Version :10

• Sequence 1: NP_001350857.1
• Gene: yki / 37851
• FlyBaseID: FBgn0034970
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: XP_061505717.1
• Gene: Nedd4 / 1273805
• VectorBaseID: AGAMI1_001899
• Length: 1056
• Species: Anopheles gambiae
• Alignment Length: 436
• Identity: 102/436 - (23%)
• Similarity: 162/436 - (37%)
• Gaps: 112/436 - (25%)

  Fly    53 SNNL----VVRVNQDTDDNLQALFDSVLN----PG-------DAKRPLQLPLRMRKLPNSFF--T 100
            |||.    .|.:..:..|...|   :|.|    ||       .|..||...|..:......|  |
Mosquito   308 SNNTSMADTVSITSENGDTTAA---AVGNRSGAPGIGSPMVLAADHPLLSTLMAQSGDGGAFVAT 369

  Fly   101 PPAP-SHSRANSADSTYDAGSQSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSP---------- 154
            |..| |..|.:.|:.|.......|:     |||.....|.:.|.     .|:|:|
Mosquito   370 PERPASAPRGDDAEPTVGLSPSPSV-----ASIASSGAGGTSIR-----PIRPAPPPPPGGGGGG 424

  Fly   155 ---QHSRLA-----IHHSRARSSPASLQQNYNVRARSDAAAANNPNANPSS------QQQPAGPT 205
               ..:|.:     :...|.||||.|.:........:.:..|.:....||:      .:|| ..:
Mosquito   425 SSASSARASPVGTPVPSQRRRSSPGSSESAQATAIEASSGEAGDTTPGPSAPIATADDEQP-NAS 488

  Fly   206 FPENSAQEFPSGAP----------ASSAIDLDAMNTCMSQDIPMSMQTVHKKQRSYDVISPIQLN 260
            .|.|.:.|  .|||          |:|:|..: .....:.:.|.:...|.....|:.........
Mosquito   489 APVNGSAE--GGAPSTVPREVSETATSSIGSE-QTAATTPNRPDTAVAVQPTSPSHPTTPAPAAQ 550

  Fly   261 RQLGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQ---NDVLQTTKQ 322
            .....|||||.....::|::::::|..|:|.|.|||..        :|..|..   :|.:.....
Mosquito   551 PNATGLPPGWAVQVASNGRLFFIDHINKTTSWVDPRTG--------LASTIPSAAGSDGVAGGGA 607

  Fly   323 TTTS-----------TIANNLGPLPDGWEQAVTESGDLYFINHIDRTTSWNDPRMQ----SGLSV 372
            .:|:           :..:||||||:|||:.|...|..:||:|..|||.|:|||:.    :|.:|
Mosquito   608 GSTAGSGHGSRGDSRSSDDNLGPLPEGWEERVHSDGRTFFIDHNTRTTQWDDPRLSNPKIAGQAV 672

  Fly   373 ----------------LDCPDNLVSSLQIEDNLCSNLFNDAQAIVN 402
                            |..|.|:.:.:.|:....| :..|:..::|
Mosquito   673 PYSRDYKQKYEYFKSQLQKPSNVPNKIDIKVRRAS-ILEDSYRVIN 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	47/176 (27%)
		WW	266..295	CDD:459800	10/28 (36%)
		WW	335..364	CDD:459800	14/28 (50%)
Nedd4	XP_061505717.1	None