DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yki and Plekha5

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_006506926.1	Gene:	Plekha5 / 109135	MGIID:	1923802	Length:	1270	Species:	Mus musculus

Alignment Length:	146	Identity:	37/146 - (25%)
Similarity:	55/146 - (37%)	Gaps:	40/146 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 ALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIA 329
            :||..|....|..|:::::|...|||.|..|          :..|.:......|:|
Mouse    12 SLPRSWTYGITRGGRVFFINEEAKSTTWLHP----------VTGEAVVTGHRRQST--------- 57

  Fly   330 NNLGPLPDGWEQAVTESGDLYFINHIDRTTSWNDPRMQSGLSVLDCPDNLVSSLQIEDNLCSNLF 394
                .||.|||:|.|..|..|:|||.:|..:...|               |:....:|| |..:.
Mouse    58 ----DLPTGWEEAYTFEGARYYINHNERKVTCKHP---------------VTGQPSQDN-CIFVV 102

  Fly   395 NDAQAIVNPPSSHKPD 410
            || |.:....|..|.:
Mouse   103 ND-QTVATMTSEDKKE 117

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	35/138 (25%)
		WW	266..295	CDD:395320	10/28 (36%)
		WW	335..364	CDD:395320	13/28 (46%)
Plekha5	XP_006506926.1	WW	13..42	CDD:366073	10/28 (36%)
		WW	59..88	CDD:366073	13/28 (46%)
		PH_PEPP1_2_3	165..268	CDD:270068
		Smc	<623..>864	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900