Protein Alignment yki and HUWE1

DIOPT Version :9

• Sequence 1: NP_001350857.1
• Gene: yki / 37851
• FlyBaseID: FBgn0034970
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: XP_016884680.1
• Gene: HUWE1 / 10075
• HGNCID: 30892
• Length: 4501
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 64/373 - (17%)
• Similarity: 126/373 - (33%)
• Gaps: 106/373 - (28%)

  Fly    27 TMSASSNTNSLIEKEIDDEDMLSPIKSN---NLVVRVNQDTDDNLQALFDSVLNPGDAKRPLQ-- 86
            |:.:.|:|..|.:.....:..|..:.:|   .:.|....:...|...:...:|.|..|...||
Human  2656 TLGSGSSTTRLTQGIGRSQRTLRQLTANTGHTIHVHYPGNRQPNPPLILQRLLGPSAAADILQLS 2720

  Fly    87 --LPLRMR--------------------KLPNSFFTPPAPSHSRANS------------------ 111
              |||:.|                    :|.:.||...:.:.|:|.:
Human  2721 SSLPLQSRGRARLLVGNDDVHIIARSDDELLDDFFHDQSTATSQAGTLSSIPTALTRWTEECKVL 2785

  Fly   112 -ADSTYDAGSQSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSPQHSRLAIHHSRARSSPASLQQ 175
             |:|.:|..|...::|.|....::.          .:|:.:...:..:||...::........::
Human  2786 DAESMHDCVSVVKVSIVNHLEFLRD----------EELEERREKRRKQLAEEETKITDKGKEDKE 2840

  Fly   176 NYNVRARSDAAAANNPNANPSSQQQPAGPTFPENSAQEFPSGAPASSAIDLDAMNTCMSQ----- 235
            |.:..|:..|:.:|:......|...|...::|..     ||...|:::...:.:.|..|.
Human  2841 NRDQSAQCTASKSNDSTEQNLSDGTPMPDSYPTT-----PSSTDAATSESKETLGTLQSSQQQPT 2900

  Fly   236 --------DIPMSMQT-VHKKQRSYDVISPIQLNRQLGALPPGWEQAKTNDGQIYYLNHTTKSTQ 291
                    ::|..:|: ..:...|..::.|:: ..:||...|..|               .::||
Human  2901 LPTPPALGEVPQELQSPAGEGGSSTQLLMPVE-PEELGPTRPSGE---------------AETTQ 2949

  Fly   292 WE---DPRIQYRQQQQILMAERIKQNDVLQTTKQ------TTTSTIAN 330
            .|   .|.|      ..|..||.:.:|.|.....      ..||::|:
Human  2950 MELSPAPTI------TSLSPERAEDSDALTAVSSQLEGSPMDTSSLAS 2991

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	17/79 (22%)
		WW	266..295	CDD:395320	5/31 (16%)
		WW	335..364	CDD:395320
HUWE1	XP_016884680.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900