DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yki and magi2b

DIOPT Version :9

Sequence 1:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_021326360.1	Gene:	magi2b / 100001810	ZFINID:	ZDB-GENE-141211-6	Length:	1171	Species:	Danio rerio

Alignment Length:	228	Identity:	61/228 - (26%)
Similarity:	99/228 - (43%)	Gaps:	59/228 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 ARSDAAAANNPNANPSSQQQPA-GPTFPENSAQEFP----SG---APASSAIDLDAMNTCMSQDI 237
            ||..|......|.:.|:.::.: .|  ||...:|.|    :|   .|.||  :.:..:|..|.|:
Zfish    44 ARPSAEGKRKRNKSVSNMEKDSIEP--PEEEEEESPIINGNGIAITPESS--EHEDKSTDASGDV 104

  Fly   238 PM--------SMQTVHKKQRSYDV-ISP--IQLNRQLGALPPGWEQAKTNDGQIYYLNHTTKSTQ 291
            |:        ::......:...|. .||  :|.|..:|:||..||.|.|..|::|:::|.||:|.
Zfish   105 PVQPCPPETPTLTATDVPEEEGDAPKSPQDLQENDDMGSLPDNWEMAYTEKGEVYFIDHNTKTTS 169

  Fly   292 WEDPRIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIANNLGPLPDGWEQAVTESGDLYFINHID 356
            |.|||          :|::.|..:..:..:             ||.|||:........|:::||:
Zfish   170 WLDPR----------LAKKAKPPEECEEDE-------------LPYGWEKIDDPIYGSYYVDHIN 211

  Fly   357 RTTSWNDP------------RMQS-GLSVLDCP 376
            |.|.:.:|            :||| |||.|..|
Zfish   212 RRTQFENPVLEAKRRIQQQQQMQSQGLSALPLP 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	38/129 (29%)
		WW	266..295	CDD:395320	13/28 (46%)
		WW	335..364	CDD:395320	10/28 (36%)
magi2b	XP_021326360.1	NK	<1..>29	CDD:327404
		MAGI_u1	35..96	CDD:318800	14/55 (25%)
		WW	145..175	CDD:238122	15/39 (38%)
		WW	190..219	CDD:306827	10/28 (36%)
		PDZ	266..349	CDD:214570
		PDZ	451..531	CDD:214570
		PDZ	622..708	CDD:214570
		PDZ_signaling	743..832	CDD:238492
		PDZ_signaling	1034..1114	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000