Protein Alignment Rap2l and RAP2B

DIOPT Version :9

• Sequence 1: NP_477402.1
• Gene: Rap2l / 37850
• FlyBaseID: FBgn0283666
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_002877.2
• Gene: RAP2B / 5912
• HGNCID: 9862
• Length: 183
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 125/184 - (67%)
• Similarity: 148/184 - (80%)
• Gaps: 3/184 - (1%)

  Fly     1 MREFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFA 65
            |||:||||||||||||||||||||:|.|||||||||||||||||||||||.||||||||||||||
Human     1 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFA 65

  Fly    66 SMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAE 130
            ||||||||||.|||::|||.|.|:||||..|::.|.|||..:..|::||.||.||:.:||||..|
Human    66 SMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGEREVSYGE 130

  Fly   131 GNALAQLWDCPFIEASAKDRINVNEVFATIVREMNLTQENRQKKNYCC--CTLL 182
            |.|||:.|.|||:|.|||::.:|:|:||.|||:||...:....:. ||  |.:|
Human   131 GKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEG-CCSACVIL 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	105/148 (71%)
RAP2B	NP_002877.2	Rap2	3..165	CDD:133376	117/161 (73%)
		Effector region. /evidence=ECO:0000305	32..40		7/7 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	236	1.000	Domainoid score	I2343
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H55701
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3253
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48239
OrthoDB	1	1.010	-	-		D1353024at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	1	1.000	-	-		otm40900
orthoMCL	1	0.900	-	-		OOG6_106771
Panther	1	1.100	-	-	O	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3491
SonicParanoid	1	1.000	-	-		X266
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870