Protein Alignment Rap2l and RAP2A

DIOPT Version :9

• Sequence 1: NP_477402.1
• Gene: Rap2l / 37850
• FlyBaseID: FBgn0283666
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_066361.1
• Gene: RAP2A / 5911
• HGNCID: 9861
• Length: 183
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 125/183 - (68%)
• Similarity: 148/183 - (80%)
• Gaps: 3/183 - (1%)

  Fly     1 MREFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFA 65
            |||:||||||||||||||||||||:|.|||||||||||||||||||||||.||||||||||||||
Human     1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFA 65

  Fly    66 SMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAE 130
            ||||||||||.|||::|||.|.|:||||..|::.|.|||..:..|::||.||.||:.:||||::|
Human    66 SMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSSE 130

  Fly   131 GNALAQLWDCPFIEASAKDRINVNEVFATIVREMNLTQENRQKKNYCC--CTL 181
            |.|||:.|.|||:|.|||.:..|:|:||.|||:||...: ..|.:.||  |.:
Human   131 GRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQ-PDKDDPCCSACNI 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	105/148 (71%)
RAP2A	NP_066361.1	Rap2	3..165	CDD:133376	117/161 (73%)
		Effector region. /evidence=ECO:0000305	32..40		7/7 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	236	1.000	Domainoid score	I2343
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3253
Isobase	1	0.950	-	0	Normalized mean entropy	S466
OMA	1	1.010	-	-		QHG48239
OrthoDB	1	1.010	-	-		D1353024at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	1	1.000	-	-		otm40900
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3491
SonicParanoid	1	1.000	-	-		X266
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.920