Protein Alignment Rap2l and DIRAS2

DIOPT Version :10

• Sequence 1: NP_477402.1
• Gene: Rap2l / 37850
• FlyBaseID: FBgn0283666
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_060064.2
• Gene: DIRAS2 / 54769
• HGNCID: 19323
• Length: 199
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 78/193 - (40%)
• Similarity: 117/193 - (60%)
• Gaps: 13/193 - (6%)

  Fly     3 EFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFASM 67
            :::|.|.|:||||||:|.::||.|.|.|.|.||:||.||:.|..|.|.|.|:|.||.|:.||.:|
Human     7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAM 71

  Fly    68 RDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGS-QPAPILLVANKFDLDCQREVSTAEG 131
            :.|.|..||.||::||:|:.|:.:::..:...|..:||. :..||:||.||.|....|||.::|.
Human    72 QRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPSREVQSSEA 136

  Fly   132 NALAQLWDCPFIEASAKDRINVNEVFATIV-----REMNL-------TQENRQKKNYCCCTLL 182
            .|||:.|.|.|:|.|||...||.|:|..::     |.::|       .|:.|::|....|.::
Human   137 EALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	66/154 (43%)
DIRAS2	NP_060064.2	ARHI_like	7..170	CDD:206711	72/162 (44%)
		Effector region. /evidence=ECO:0000255	36..44		5/7 (71%)