DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap2l and CG8519

DIOPT Version :9

Sequence 1:	NP_477402.1	Gene:	Rap2l / 37850	FlyBaseID:	FBgn0283666	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_648054.2	Gene:	CG8519 / 38745	FlyBaseID:	FBgn0035711	Length:	207	Species:	Drosophila melanogaster

Alignment Length:	180	Identity:	62/180 - (34%)
Similarity:	103/180 - (57%)	Gaps:	14/180 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTA--GTEQ 63
            :.|.|:.|:|:..||||||.|:|::..:|.:||...|:.|:.|..||..|.:.|||||.  ..::
  Fly    13 LTELKIAVIGAPSVGKSALIVRFLTKRYIGEYDHQTENRYKHEAMVDGEPVLFEILDTCPKAEDE 77

  Fly    64 FASMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKG--SQPAPILLVANKFDLDCQREV 126
            :.:..:| ::...|.:::||:|:.::|       |.|.|.|.  ....|:.|.|||.|:...|:|
  Fly    78 YPNAAEL-VQWADGLLLVYSITDRKSF-------NYIRRAKSDLQSDTPVQLCANKVDMVHLRQV 134

  Fly   127 STAEGNALAQLWDCPFIEASAKDRIN-VNEVFATIVREMNLTQENRQKKN 175
            |..||..||:.::|.|.|.||.|.:: |.|||..:.:|: |..:.:.|::
  Fly   135 SRDEGEILAKDFECKFSEVSAADHVDQVAEVFNELCKEV-LASKRKSKQS 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	54/153 (35%)
CG8519	NP_648054.2	small_GTPase	14..173	CDD:197466	59/166 (36%)
CG8519	NP_648054.2	P-loop_NTPase	17..173	CDD:304359	58/163 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452987
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740