DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap2l and Ric

DIOPT Version :9

Sequence 1:	NP_477402.1	Gene:	Rap2l / 37850	FlyBaseID:	FBgn0283666	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_001163165.1	Gene:	Ric / 36776	FlyBaseID:	FBgn0265605	Length:	264	Species:	Drosophila melanogaster

Alignment Length:	181	Identity:	84/181 - (46%)
Similarity:	124/181 - (68%)	Gaps:	8/181 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFA 65
            :|.:|:|:||.|||||||:|:||||..|::.:||||||.|:::..:|:...:|:||||||..:|.
  Fly    57 LRVYKIVILGDGGVGKSAVTLQFVSHSFLDYHDPTIEDSYQQQAVIDNEAALLDILDTAGQVEFT 121

  Fly    66 SMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAE 130
            :|||.|::.|.|||:.||:|:..:||:.|..:.:||||:.|:..|::|:|||.||:.||.|:|.|
  Fly   122 AMRDQYMRCGEGFIICYSVTDRHSFQEASEYRKLITRVRLSEDIPLVLIANKVDLESQRRVTTEE 186

  Fly   131 GNALAQLWDCPFIEASAKDRINVNEVFATIVREMNL--------TQENRQK 173
            |..||..:.|||.|.||..|..::|.|.|:|||:..        |..|.:|
  Fly   187 GRNLANQFGCPFFETSAALRHYIDEAFYTLVREIRRKEMHKALGTDSNSEK 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	72/148 (49%)
Ric	NP_001163165.1	Rit_Rin_Ric	58..229	CDD:206712	81/170 (48%)
Ric	NP_001163165.1	small_GTPase	58..223	CDD:197466	81/164 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453042
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24070
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840