DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap2l and Hras

DIOPT Version :9

Sequence 1:	NP_477402.1	Gene:	Rap2l / 37850	FlyBaseID:	FBgn0283666	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	XP_006230597.3	Gene:	Hras / 293621	RGDID:	2827	Length:	290	Species:	Rattus norvegicus

Alignment Length:	191	Identity:	83/191 - (43%)
Similarity:	123/191 - (64%)	Gaps:	13/191 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFA 65
            |.|:|:||:|:|||||||||:|.:...|:::|||||||.|||::.:|...|:|:||||||.|:::
  Rat   102 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 166

  Fly    66 SMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAE 130
            :|||.|::.|.||:.::::.|.::|:||...:..|.|||.|...|::||.||.|| ..|.|.:.:
  Rat   167 AMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-AARTVESRQ 230

  Fly   131 GNALAQLWDCPFIEASAKDRINVNEVFATIVREMNLTQENRQKKN----------YCCCTL 181
            ...||:.:..|:||.|||.|..|.:.|.|:|||  :.|...:|.|          .|.|.|
  Rat   231 AQDLARSYGIPYIETSAKTRQGVEDAFYTLVRE--IRQHKLRKLNPPDESGPGCMSCKCVL 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	67/148 (45%)
Hras	XP_006230597.3	H_N_K_Ras_like	104..265	CDD:133338	76/163 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810