DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap2l and Rras

DIOPT Version :9

Sequence 1:	NP_477402.1	Gene:	Rap2l / 37850	FlyBaseID:	FBgn0283666	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_033127.1	Gene:	Rras / 20130	MGIID:	98179	Length:	218	Species:	Mus musculus

Alignment Length:	188	Identity:	81/188 - (43%)
Similarity:	117/188 - (62%)	Gaps:	10/188 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFASMRD 69
            |:||:|.|||||||||:||:...|:..|||||||.|.|...||..|..|:||||||.|:|.:||:
Mouse    31 KLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMRE 95

  Fly    70 LYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAEGNAL 134
            .|::.|:||::::::.:.|:|.::..:...|.|||.....||:||.||.||:.||:|..:|.::.
Mouse    96 QYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSF 160

  Fly   135 AQLWDCPFIEASAKDRINVNEVFATIVREMNLTQEN----------RQKKNYCCCTLL 182
            :......:.|||||.|:||:|.|..:||.:...||.          |:|...|.|.||
Mouse   161 SASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKDGGCPCVLL 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	65/148 (44%)
Rras	NP_033127.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		M_R_Ras_like	28..191	CDD:133345	73/159 (46%)
		Effector region	58..66		7/7 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810