DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rap2l and rap-3

DIOPT Version :9

Sequence 1:	NP_477402.1	Gene:	Rap2l / 37850	FlyBaseID:	FBgn0283666	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_502095.2	Gene:	rap-3 / 182417	WormBaseID:	WBGene00004309	Length:	205	Species:	Caenorhabditis elegans

Alignment Length:	200	Identity:	83/200 - (41%)
Similarity:	120/200 - (60%)	Gaps:	19/200 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MREFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFA 65
            |:|:|:||||:|||||||||:|:|.|.|:..||.||||.|||..:||:....||||||||||||.
Worm     1 MKEYKIVVLGNGGVGKSALTLQYVQGIFVHTYDATIEDSYRKLSKVDAENARLEILDTAGTEQFT 65

  Fly    66 SMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAE 130
            .||:.|.:...||::::||....||:::......|..::|.: .|::||.||.||...|:|..:|
Worm    66 GMRETYYRTAQGFVLVFSLAETSTFENLKQTFTDIIAIRGKE-VPMILVGNKSDLAETRQVDESE 129

  Fly   131 GNALAQLWDCPFIEASAKDRINVNEVF---ATIVREMNLTQENRQK------------KNY---C 177
            .:..|:....|:.|.||:...||:|||   |.::::.......|:|            ||:   |
Worm   130 AHNFAEKLKIPYFETSARLNQNVSEVFEECAVLIQKSAKPNIERRKWSSESEIGDKKCKNWLRSC 194

  Fly   178 CCTLL 182
            ||.|:
Worm   195 CCCLI 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	64/151 (42%)
rap-3	NP_502095.2	small_GTPase	2..166	CDD:197466	74/164 (45%)
rap-3	NP_502095.2	Ras	5..158	CDD:206642	72/153 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1353024at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24070
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920