DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rap2l and ras-1

DIOPT Version :9

Sequence 1:	NP_477402.1	Gene:	Rap2l / 37850	FlyBaseID:	FBgn0283666	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_496623.1	Gene:	ras-1 / 174875	WormBaseID:	WBGene00004310	Length:	212	Species:	Caenorhabditis elegans

Alignment Length:	168	Identity:	75/168 - (44%)
Similarity:	113/168 - (67%)	Gaps:	0/168 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFASMRD 69
            ::||:|.|||||||||:||:...|::.|||||||.|.|:..||...|.||||||||.|:|::||:
Worm    19 RIVVVGGGGVGKSALTIQFIQRYFVQDYDPTIEDSYTKQCFVDEDLCKLEILDTAGQEEFSTMRE 83

  Fly    70 LYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAEGNAL 134
            .|::.|.||::::::|:..:|:::..:..:|.|:|.....||:||.||.||:.:|.|:..|...|
Worm    84 QYLRTGSGFLIVFAVTDRNSFEEVKKLHELICRIKDRDDFPIILVGNKADLENERHVARHEAEEL 148

  Fly   135 AQLWDCPFIEASAKDRINVNEVFATIVREMNLTQENRQ 172
            |.....|::|.|||.|.||:|.|..|||.:...|.:.:
Worm   149 AHRLSIPYLECSAKIRKNVDEAFFDIVRLVRKYQHDER 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rap2l	NP_477402.1	Rap2	16..165	CDD:133376	67/148 (45%)
ras-1	NP_496623.1	small_GTPase	30..181	CDD:197466	67/150 (45%)
ras-1	NP_496623.1	M_R_Ras_like	30..179	CDD:133345	67/148 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910