DRSC/TRiP Functional Genomics Resources

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Protein Alignment RpL39 and EPRS1

DIOPT Version :9

Sequence 1:NP_477314.1 Gene:RpL39 / 37849 FlyBaseID:FBgn0023170 Length:51 Species:Drosophila melanogaster
Sequence 2:NP_004437.2 Gene:EPRS1 / 2058 HGNCID:3418 Length:1512 Species:Homo sapiens


Alignment Length:31 Identity:9/31 - (29%)
Similarity:15/31 - (48%) Gaps:9/31 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 AKKLKQNRSVP----QWVRLRTGNTIRYNAK 40
            ||.::.:|.:|    ||.     |.:|:..|
Human  1131 AKWVQSHRDLPIKLNQWC-----NVVRWEFK 1156

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RpL39NP_477314.1 Ribosomal_L39 <20..50 CDD:395670 7/25 (28%)
EPRS1NP_004437.2 PLN02907 13..711 CDD:215492
GST_C_GluProRS_N 74..157 CDD:198342
Glutamate--tRNA ligase 164..759
tRNA-synt_1c 197..502 CDD:279135
'HIGH' region 204..214
'KMSKS' region 432..436
tRNA-synt_1c_C 504..681 CDD:281883
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 709..744
WHEP-TRS 753..805 CDD:278865
3 X 57 AA approximate repeats 760..956
WHEP-TRS 826..878 CDD:278865
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 869..900
WEPRS_RNA 904..952 CDD:238473
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 956..1012
Charged 959..991
Proline--tRNA ligase 1007..1512 9/31 (29%)
PRK08661 1019..1512 CDD:236327 9/31 (29%)
ProRS_core_arch_euk 1023..1286 CDD:238401 9/31 (29%)
L-proline binding. /evidence=ECO:0000269|PubMed:24100331, ECO:0007744|PDB:4K87 1121..1123
ProRS_anticodon_zinc 1292..1512 CDD:238439
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0008
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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