DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF5 and iff-1

DIOPT Version :9

Sequence 1:	NP_611878.1	Gene:	eEF5 / 37846	FlyBaseID:	FBgn0285952	Length:	159	Species:	Drosophila melanogaster
Sequence 2:	NP_001255020.1	Gene:	iff-1 / 176373	WormBaseID:	WBGene00002064	Length:	195	Species:	Caenorhabditis elegans

Alignment Length:	154	Identity:	93/154 - (60%)
Similarity:	120/154 - (77%)	Gaps:	5/154 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DDQFETTDSGASTTYPMQCSALRKNGFVMLKSRPCKIVEMSTSKTGKHGHAKVHMVGIDIFSNKK 69
            ::||::.:|||:.|:|.||||||||..||::.||||||||||||||||||||||||.||||:.||
Worm    42 EEQFDSAESGAAATFPKQCSALRKNEHVMIRGRPCKIVEMSTSKTGKHGHAKVHMVAIDIFTTKK 106

  Fly    70 YEDICPSTHNMDVPNVKREDLQLIAISDDSFLTLM-TESGDLREDLKVPEGELGEQLR--LDFDS 131
            .|||||||||||||.|||.:..|::| :|.|.:|| .||.:|::|||:|||:||..:|  |:.|.
Worm   107 LEDICPSTHNMDVPVVKRREYILMSI-EDGFCSLMDPESCELKDDLKMPEGDLGNTIREALEKDE 170

  Fly   132 GKDLLCTVLKACGEECVIAIKTNT 155
            | .:|..|:.|||||.::..|.:|
Worm   171 G-SVLVQVVAACGEEAILGYKIST 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF5	NP_611878.1	PLN03107	1..152	CDD:215580	91/149 (61%)
eEF5	NP_611878.1	eIF-5a	84..152	CDD:279611	31/70 (44%)
iff-1	NP_001255020.1	PLN03107	40..190	CDD:215580	91/149 (61%)
iff-1	NP_001255020.1	S1_eIF5A	122..192	CDD:239914	32/71 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161029
Domainoid	1	1.000	137	1.000	Domainoid score	I3033
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100947
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2628
Isobase	1	0.950	-	0	Normalized mean entropy	S164
OMA	1	1.010	-	-		QHG53968
OrthoDB	1	1.010	-	-		D1370513at2759
OrthoFinder	1	1.000	-	-		FOG0001335
OrthoInspector	1	1.000	-	-		otm14616
orthoMCL	1	0.900	-	-		OOG6_100628
Panther	1	1.100	-	-	LDO	PTHR11673
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2157
SonicParanoid	1	1.000	-	-		X827
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890