Protein Alignment ppk29 and ASIC3

DIOPT Version :9

• Sequence 1: NP_001097442.2
• Gene: ppk29 / 37844
• FlyBaseID: FBgn0034965
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_064717.1
• Gene: ASIC3 / 9311
• HGNCID: 101
• Length: 549
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 69/344 - (20%)
• Similarity: 124/344 - (36%)
• Gaps: 87/344 - (25%)

  Fly   148 EIYFRG-----ELVTDCE--------EIFKFHVTEMGYCFLANNLLDYDSIEEMPLRYSSLDNNR 199
            ::|.|.     :::.||.        |.|....|.||.|:..|:  ..|..|.:......:.|..
Human   148 QLYARAGHSLDDMLLDCRFRGQPCGPENFTTIFTRMGKCYTFNS--GADGAELLTTTRGGMGNGL 210

  Fly   200 SLRL------YM---RSSVMYKYE----MYVNSPEDLPFFNSLTYTISTDPTTY-AFNVEEIH-- 248
            .:.|      |:   |.:....:|    :.::|.|:.|..:.|...:|....|: :...:::.
Human   211 DIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFL 275

  Fly   249 --------------NHEGVIDEPISQRKCKFPSESSIEGFPYSFSACMSIIRSEFEMKTCDCSL- 298
                          |:|....:|:....   ||.|.    ||:...|.....:.:..:.|.|.:
Human   276 PPPWGDCSSASLNPNYEPEPSDPLGSPS---PSPSP----PYTLMGCRLACETRYVARKCGCRMV 333

  Fly   299 FNPKD---------RNESLYCGLQHADCLIKEGFATRVKEYVGSSTVCLPSCVEQQISLVGVITE 354
            :.|.|         :|    |.....|.:::       |:.......|..:...:::|:|.:.:.
Human   334 YMPGDVPVCSPQQYKN----CAHPAIDAMLR-------KDSCACPNPCASTRYAKELSMVRIPSR 387

  Fly   355 NGT------LYNNNTQITEIQIASP---PTVRYERKVTQTKL----DLIVGIGSVAGLFFGASLL 406
            ...      |..:...|.|..:|..   ..:.|| .|.|.|.    :|:..||...|||.|||||
Human   388 AAARFLARKLNRSEAYIAENVLALDIFFEALNYE-TVEQKKAYEMSELLGDIGGQMGLFIGASLL 451

  Fly   407 NLLEIISYFIKKLKTMIFG 425
            .:|||:.|..:..:..:.|
Human   452 TILEILDYLCEVFRDKVLG 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk29	NP_001097442.2	ASC	123..415	CDD:279230	67/332 (20%)
ASIC3	NP_064717.1	ASC	20..534	CDD:295594	69/344 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..307		5/24 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152189
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850