Protein Alignment ppk29 and SCNN1B

DIOPT Version :9

• Sequence 1: NP_001097442.2
• Gene: ppk29 / 37844
• FlyBaseID: FBgn0034965
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_016879014.1
• Gene: SCNN1B / 6338
• HGNCID: 10600
• Length: 659
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 85/370 - (22%)
• Similarity: 137/370 - (37%)
• Gaps: 81/370 - (21%)

  Fly    97 SFTRMIYEYAFLNPNNIFTKEPTK---NTSYPYNFNILDIRRKMFPTNCTECFKEIYFRGELVTD 158
            |.|:.:.|:..|...|||.:.|.:   ..|||....||.......|.|... |..|::  ....:
Human   229 SATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRN-FTSIFY--PHYGN 290

  Fly   159 CEEIFKFHVTEM-------GYCFLANNLLDYDSIEEMPLRYSSLDNNRSLRLYMRSSVMYKYEMY 216
            | .||.:.:||.       |..|....:||....:.:|.    |.:...:||.:.....|
Human   291 C-YIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPF----LASTAGVRLMLHEQRSY----- 345

  Fly   217 VNSPEDLPFF-NSLTYTISTDPTTYAFNVEEIHNHEGVIDEPISQRKCKF-PSESSIEGF----- 274
                   ||. :...|.:|...|:....|:::..    :.||.|  .|.. .||..::.|
Human   346 -------PFIRDEGIYAMSGTETSIGVLVDKLQR----MGEPYS--PCTVNGSEVPVQNFYSDYN 397

  Fly   275 -PYSFSACMSIIRSEFEMKTCDCSLF-NPKDRNESLYCGLQH----ADCL--IKEGFATRVKEYV 331
             .||..||:.....:..::.|:|..: .|..|.|. ||..:.    |.|.  ::...|.| :..:
Human   398 TTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEK-YCNNRDFPDWAHCYSDLQMSVAQR-ETCI 460

  Fly   332 GSSTVCLPSCVEQQ----ISLVGVITENG------TLYNNNTQITEIQIASPPTVRYE------- 379
            |   :|..||.:.|    ||:....:|..      .|.....|.|.|.::....|:..
Human   461 G---MCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFN 522

  Fly   380 -RKVTQTKLDLIV----GIGSVAGLFFGASLLNLL---EIISYFI 416
             |.:.::..:.||    .:|...|.:.|.|:|.|:   |||..|:
Human   523 YRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFV 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk29	NP_001097442.2	ASC	123..415	CDD:279230	76/338 (22%)
SCNN1B	XP_016879014.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152147
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750