DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk29 and asic1c

DIOPT Version :9

Sequence 1:	NP_001097442.2	Gene:	ppk29 / 37844	FlyBaseID:	FBgn0034965	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	XP_021325802.1	Gene:	asic1c / 407670	ZFINID:	ZDB-GENE-040513-3	Length:	562	Species:	Danio rerio

Alignment Length:	494	Identity:	102/494 - (20%)
Similarity:	177/494 - (35%)	Gaps:	130/494 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GFIRSFVENKG----LLWIFVIGIS-----GWSTVSILVLLKTRYETDSTTIGVSTAYSRWIN-- 64
            |...:|..:|.    |.|:..:.:.     .||...||.||.  |.      .|:..|..|.|
Zfish    49 GLKHAFSPHKSKTQRLFWLLALLVCLGLLFTWSWNRILYLLS--YP------AVTKIYMVWSNNM 105

  Fly    65 TFPSIGICLTKSRAFNEFKAMMREYFQEDFAFSFTRMIYEYAFLNPNNIFTKEPTKNTSYPYN-- 127
            |||:|..|       |:.:..:....::|..:|.    |....|:.|:...::......:..:
Zfish   106 TFPAITFC-------NQNRLRVSSLTRDDLYYSG----YWMDILHLNHTLNRQSVSMLKHSRHRE 159

  Fly   128 --FNILDIRRKMFP----TNCTECFK-----------EIYFRGELVTDCEEIFKFHVTEMGYCFL 175
              .::||......|    .|.||...           |..||||..|  .:.|....|..|.|:.
Zfish   160 RLLHLLDFSHYSPPPDQSLNTTEMIDRLGHQLQDMLLECRFRGENCT--YKNFTPIYTRYGKCYT 222

  Fly   176 ANN---------------------LLDYDSIEEMPLRYSSLDNNRSLRLYMRSSVMYKYE----M 215
            .|:                     :||....|.:|: :...|..             .||    :
Zfish   223 FNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPV-WGDTDET-------------SYEAGIKV 273

  Fly   216 YVNSPEDLPFFNSLTYTISTDPTTYAFNVEEIHNHEGVIDEPISQRKCKFPSESSIEGFPYSFSA 280
            .::|.::.||.:.|.:.::....|:....:::     ::..|.....|:.....|.....||.:|
Zfish   274 QIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQL-----LLYLPPPWGDCRSAPMDSEYFSTYSITA 333

  Fly   281 CMSIIRSEFEMKTCDCSLFNPKDRNESLYC-GLQHADC-------LIKEGFATRVKEYVGSSTVC 337
            |.....:.:.::.|:|.:.:..  ..|..| ..|:.||       |:::.     .:|....|.|
Zfish   334 CRIDCETRYLLENCNCRMVHMP--GTSTVCTPEQYKDCADPALDFLVEKD-----NDYCVCDTPC 391

  Fly   338 LPSCVEQQISLVGVITENGTLY------------NNNTQITEIQIASPPTVRYERKVTQTKLDLI 390
            ..:...:::|:|.:.::....|            .:|..:.:|...:   :.|| |:.|.|...:
Zfish   392 NMTRYGKELSMVKIPSKASAKYLAKKFNKTEQYITDNILVLDIFFEA---LNYE-KIEQKKAYEV 452

  Fly   391 VG----IGSVAGLFFGASLLNLLEIISYFIKKLKTMIFG 425
            .|    ||...|||.|||:|.:|||..|..:.||..|.|
Zfish   453 AGLLGDIGGQMGLFIGASVLTILEIFDYLYEVLKDKILG 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk29	NP_001097442.2	ASC	123..415	CDD:279230	70/359 (19%)
asic1c	XP_021325802.1	ASC	34..531	CDD:322155	102/494 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586671
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950