Protein Alignment ppk29 and asic2

DIOPT Version :10

• Sequence 1: NP_001097442.2
• Gene: ppk29 / 37844
• FlyBaseID: FBgn0034965
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_005164179.1
• Gene: asic2 / 407669
• ZFINID: ZDB-GENE-040513-4
• Length: 564
• Species: Danio rerio
• Alignment Length: 504
• Identity: 104/504 - (20%)
• Similarity: 172/504 - (34%)
• Gaps: 169/504 - (33%)

  Fly     2 WRKSVMNFRGFIRSFVENKGLLWIFVIGISGWSTVSILVLLKTRYETDSTTIGVSTAYSRWIN-- 64
            |..:.....|.:.|:..|:.|.|:      .:.|       .||..|:            |..
Zfish    92 WMIAFCTCLGLLLSWSSNRLLHWL------AFPT-------HTRVHTE------------WAKEL 131

  Fly    65 TFPSIGIC---------LTKSRAF------------NEFKAMMREYFQEDFAFSFTRMIYEYAFL 108
            .||::.||         ||||..:            ...:.::.:..|:|....|:::.....||
Zfish   132 AFPTVTICNNNPVRLYHLTKSDLYFAGHWLGLLLANRTARPLVLDLLQDDRRGWFSKLSDFRLFL 196

  Fly   109 NPNNIFTKEPTKNTSYPYNFNILDIRRKMFPTNCTECFKEIYFRGELVTDC-EEIFKFHVTEMGY 172
            .|...      :.||..:    :|............|    .:|||   .| ...|....|..|.
Zfish   197 PPRRF------EGTSLEF----MDRLGHQLEDMLLAC----KYRGE---PCGAHNFSTVFTRYGK 244

  Fly   173 CFLANNLLDYDSIEEMPLRYSSLDNNRSLRLYMRSSVMYKYEMYVNSPED--LPFFNSLTYTIST 235
            |::                :::.:..::||..|:.......|:.::..:|  ||.:.      .|
Zfish   245 CYM----------------FNAAEEGKTLRTTMKGGTGNGLEIMLDIQQDEYLPVWG------ET 287

  Fly   236 DPTTYAFNVE-EIHN-------HE---GVID------EPISQRKCKFP-------SESSIEGF-- 274
            :.|.:...|. :||:       ||   ||..      ....||....|       |.:...|.
Zfish   288 EETAFEAGVRVQIHSQAEPPFVHELGFGVAPGFQTFVATQEQRLTYLPPPWGECVSRALDSGLFQ 352

  Fly   275 PYSFSACMSIIRSEFEMKTCDCSL-FNPKDRNESLYC-GLQHADCLIKEGFATRVKEYVGSSTVC 337
            .||.|||.....:.:.::.|:|.: :.|.|   |.|| ..|:.||  .|.....:....|::.:|
Zfish   353 VYSVSACRIECETRYIVENCNCRMVYMPGD---SPYCTPEQYKDC--AEPALAALSAVEGTNCIC 412

  Fly   338 LPSCVEQQISLVGVITENGTLYNNNTQITEIQIASPPTVRY-ERKVTQTK---------LD---- 388
            ...|             |.|.||.  :::.::|.|..:.|| |:|..:::         ||
Zfish   413 RSPC-------------NMTRYNK--ELSMVKIPSKTSARYLEKKFNRSEKYITDNILVLDVFFE 462

  Fly   389 -----------------LIVGIGSVAGLFFGASLLNLLEIISYFIKKLK 420
                             |:..||...|||.|||:|.|||:..|..:.:|
Zfish   463 ALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTLLELFDYAYEVVK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk29	NP_001097442.2	ASC	8..415	CDD:459966	101/491 (21%)
asic2	XP_005164179.1	ENaC	71..538	CDD:273304	104/504 (21%)