DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk29 and Scnn1g

DIOPT Version :9

Sequence 1:	NP_001097442.2	Gene:	ppk29 / 37844	FlyBaseID:	FBgn0034965	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_058742.2	Gene:	Scnn1g / 24768	RGDID:	3641	Length:	650	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	75/372 - (20%)
Similarity:	130/372 - (34%)	Gaps:	102/372 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 IYEYAFLNPNNIFTKEPTK---NTSYPYNFNILDIRRKMFPTNCTECFKEIYFRGELVTDCEEIF 163
            |.|:..|:..||..:.|.:   |.||                :..|.....:|.| :..|.....
  Rat   227 IQEWYKLHYMNIMAQVPLEKKINMSY----------------SAKELLVTCFFDG-MSCDARNFT 274

  Fly   164 KFHVTEMGYCFLANNLLDYDSIEEMPLRYSSLDNNRSLRLYMRSSVMYKYEMYVNSPEDLPFFNS 228
            .||....|.|:..||.      |...:..:|:..         |....:..:|:|..|..||..|
  Rat   275 LFHHPMYGNCYTFNNK------ENATILSTSMGG---------SEYGLQVILYINEDEYNPFLVS 324

  Fly   229 LT--YTISTDPTTYAFNVEEI--------------HNHEGV-IDEPISQRKCKFPSE----SSIE 272
            .|  ..:......|.| :|::              |..|.. :.||.||  |.....    ::|.
  Rat   325 STGAKVLIHQQNEYPF-IEDVGMEIETAMSTSIGMHLTESFKLSEPYSQ--CTEDGSDVPVTNIY 386

  Fly   273 GFPYSFSACMSIIRSEFEMKTCDCSLFNPKDRNESLYCGL-QHADCL-----IKEGFATRVKEYV 331
            ...||...|:........::.|.|:.::......:.||.. ||.:.:     :.:.|   |:|.:
  Rat   387 NAAYSLQICLYSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLYQAF---VREEL 448

  Fly   332 GSSTVCLPSCVEQQIS----------------LVGVIT-ENGTLYN---NNTQITEIQIASPPTV 376
            |..:||..||..::.:                |:.|:| :.....|   |.|.:.::.|.
  Rat   449 GCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTDLAKLLIF----- 508

  Fly   377 RY----ERKVTQTKLD----LIVGIGSVAGLFFGASLLNLLEIISYF 415
             |    :|.:.::..:    |:...|...||:...|::.::|||..|
  Rat   509 -YKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVF 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk29	NP_001097442.2	ASC	123..415	CDD:279230	67/346 (19%)
Scnn1g	NP_058742.2	ENaC	24..631	CDD:273304	75/372 (20%)
Scnn1g	NP_058742.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	577..628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345688
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840