Protein Alignment ppk29 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_001097442.2
• Gene: ppk29 / 37844
• FlyBaseID: FBgn0034965
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_035454.2
• Gene: Scnn1a / 20276
• MGIID: 101782
• Length: 700
• Species: Mus musculus
• Alignment Length: 536
• Identity: 92/536 - (17%)
• Similarity: 176/536 - (32%)
• Gaps: 199/536 - (37%)

  Fly    22 LLWIFVIGISGWSTVSILVLLKTRYETDSTTIGVSTAYSRWINTFPSIGICLTKSRAFNEFKAMM 86
            :||:...|:..|.    ..||...|.:...::.::....:.:  ||::.:|......:.|.|..:
Mouse   115 VLWLCTFGMMYWQ----FALLFEEYFSYPVSLNINLNSDKLV--FPAVTVCTLNPYRYTEIKEDL 173

  Fly    87 REY--FQEDFAFSFTRMIYEYAFLNPNNIFTKE-------------------------------- 117
            .|.  ..|...|.    :|:|     |:.:|::
Mouse   174 EELDRITEQTLFD----LYKY-----NSSYTRQAGGRRRSTRDLRGALPHPLQRLRTPPPPNPAR 229

  Fly   118 PTKNTSYPYNFNILDIRRK-------MFPTNCTECFKEIYFRGELVTDCEEIFKFHVTEMGYCFL 175
            ..::.|.....|...:.||       :...|.::||.:.|..|  |....|.::||     |..:
Mouse   230 SARSASSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSG--VDAVREWYRFH-----YINI 287

  Fly   176 ANNLLDYD-SIEEMPL-------RYSSLDNNRSLRLYMRSSVMYKYEMYVNS------------P 220
            .:.|.|.. ::||..|       |::....|::      :...:.:.||.|.            .
Mouse   288 LSRLPDTSPALEEEALGSFIFTCRFNQAPCNQA------NYSQFHHPMYGNCYTFNNKNNSNLWM 346

  Fly   221 EDLPFFNS-LTYTISTDPTTY--------------------AFNVEEIHNHEGVIDEPISQRK-- 262
            ..:|..|: |:.|:.|:...:                    ||..:...|....::..||.||
Mouse   347 SSMPGVNNGLSLTLRTEQNDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNVRPGVETSISMRKEA 411

  Fly   263 ----------CK-----------FPSESSIEGFPYSFSACMSIIRSEFEMKTCDCS-LFNPKDRN 305
                      |.           :||:       |:...|:.....|..:|.|.|: :|.||.:
Mouse   412 LDSLGGNYGDCTENGSDVPVKNLYPSK-------YTQQVCIHSCFQENMIKKCGCAYIFYPKPK- 468

  Fly   306 ESLYCGLQHADCLIKEGF--------ATRVKEYVGSSTVCLPSC--------------------- 341
                 |::..|.|.:..:        |....:.:|..:.|...|
Mouse   469 -----GVEFCDYLKQSSWGYCYYKLQAAFSLDSLGCFSKCRKPCSVTNYKLSAGYSRWPSVKSQD 528

  Fly   342 -VEQQISLVGVITENGTLYNNNTQITEIQI----------ASPPTVRYERKVTQTKLDLIVGIGS 395
             :.:.:||    ..|.|:.|....:.::.|          :..|:|        |.:.|:..:||
Mouse   529 WIFEMLSL----QNNYTINNKRNGVAKLNIFFKELNYKTNSESPSV--------TMVSLLSNLGS 581

  Fly   396 VAGLFFGASLLNLLEI 411
            ...|:||:|:|:::|:
Mouse   582 QWSLWFGSSVLSVVEM 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk29	NP_001097442.2	ASC	123..415	CDD:279230	73/401 (18%)
Scnn1a	NP_035454.2	ENaC	80..677	CDD:273304	92/536 (17%)
		deg-1	88..600	CDD:273309	92/536 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842270
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750