Protein Alignment ppk29 and Asic1

DIOPT Version :10

• Sequence 1: NP_001097442.2
• Gene: ppk29 / 37844
• FlyBaseID: FBgn0034965
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001276720.1
• Gene: Asic1 / 11419
• MGIID: 1194915
• Length: 559
• Species: Mus musculus
• Alignment Length: 294
• Identity: 60/294 - (20%)
• Similarity: 107/294 - (36%)
• Gaps: 80/294 - (27%)

  Fly    40 PAFKRGRQLQQMQMIILPFIPILALI--VQTSYEMIEIVSYRM--EVTEIENQVTMATDLGKVV- 99
            |:......|.:|:.:....|..|..:  :|......|.::::|  |:|:::.....|.:..:.:
Mouse   480 PSLSDSDDLDEMERLRKEHIEALRELKGLQDKLAESESLNHKMLQELTKVKQDAKSAVEESRSLR 544

  Fly   100 TRLQQERSDVAFYIYTNGMTLRRNLNDTFLETDLALDNMSSWPDISIRTIQPNNGEVTWLNMSEF 164
            ||:....   |......||.:........||.::|  .|.     |::|.||          |:.
Mouse   545 TRIHLAE---AAQKQARGMEMDYEEVIHLLEAEIA--EMK-----SLKTEQP----------SQE 589

  Fly   165 RETLQEFRANISTEDSTVPQILRWYTTANAALLEHLTNQIKDANKSGVWRFLLSFKNLLRSIESL 229
            :|.||:.:..||                   :||....:.:.|.|.    |.:|...||:.:|:
Mouse   590 KEDLQDLKKRIS-------------------VLECQLRKSEVAKKG----FQVSTGKLLQFVEA- 630

  Fly   230 DISSVYGIN-YYGRGYLKPDSYIKYVQHDILGRDLLNGSLHFVP----SLKVIYRNITLTMRS-- 287
             :.|....| ...||:   .|:.. |:...|.:.:.:..:...|    ||.|..:.:|.|:||
Mouse   631 -VQSFLSENPSASRGH---SSHYD-VKSGTLSQTVASRGVKKTPCTASSLSVEAKELTQTVRSIL 690

  Fly   288 ------YGNITQWSKTIQKNLRREGNVADARSYY 315
                  :|    |.         |...:|...||
Mouse   691 ELDCLPFG----WD---------EAYTSDGVKYY 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk29	NP_001097442.2	ASC	8..415	CDD:459966	60/294 (20%)
Asic1	NP_001276720.1	ENaC	63..541	CDD:273304	11/60 (18%)