DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sei and KAT1

DIOPT Version :9

Sequence 1:	NP_001286814.1	Gene:	sei / 37843	FlyBaseID:	FBgn0003353	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_199436.1	Gene:	KAT1 / 834666	AraportID:	AT5G46240	Length:	677	Species:	Arabidopsis thaliana

Alignment Length:	525	Identity:	122/525 - (23%)
Similarity:	226/525 - (43%)	Gaps:	77/525 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 DMITSLGGNILLDQKLQNNYYHKWTLLHYSPFKAVWDWIILILVMYTAIFTPYVAAFLLGEQDYQ 352
            |::.|||..|....||:     |..:..::|....|:..:::||:|:|...|:..||:    .|:
plant    32 DLLPSLGARINQSTKLR-----KHIISPFNPRYRAWEMWLVLLVIYSAWICPFQFAFI----TYK 87

  Fly   353 RRNSKYINSDPIVIIDLIVDVTFIVDIIINFRTTFVNSQDE-VVSHPGRIAVHYLSGWFLIDLVA 416
            :        |.|.|||.||:..|.:|||:.|...:::|... :|..|.:||:.|||.||..|:.:
plant    88 K--------DAIFIIDNIVNGFFAIDIILTFFVAYLDSHSYLLVDSPKKIAIRYLSTWFAFDVCS 144

  Fly   417 AVPFDLLLVGSDTDETTTLIGLLKTARLLRLVRVA------RKIDRYSEYGAAVLILLMATFILI 475
            ..||..|.:..:.:.:.....:|...||.||.||:      .|..|::.:......|:..|...|
plant   145 TAPFQPLSLLFNYNGSELGFRILSMLRLWRLRRVSSLFARLEKDIRFNYFWIRCTKLISVTLFAI 209

  Fly   476 AHWLACIWYAIG----NAEKSIASKNIGWLNSLAYDIQEPYFDNRTGGPSIKSRYITALYFTFTS 536
             |...|..|.|.    |..|:       |:.::..:.:|         .|:.:||:||||::.|:
plant   210 -HCAGCFNYLIADRYPNPRKT-------WIGAVYPNFKE---------ASLWNRYVTALYWSITT 257

  Fly   537 LTSVGFGNVAPNTDAEKAFTICVMLVGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRF 601
            ||:.|:|:.......|..|.|..|:....:.|.:.||::.::....|.|..:...:....||...
plant   258 LTTTGYGDFHAENPREMLFDIFFMMFNLGLTAYLIGNMTNLVVHWTSRTRTFRDSVRAASEFASR 322

  Fly   602 HQIPNPLRQRLEEY----FQHAWTYTNGIDMNSLLKGFPECLQADICLHLNRKLLTTCAAFSEAS 662
            :|:|:.::.::..:    |:     |.|:.....|...|:.:::.|..:|...::.....|...|
plant   323 NQLPHDIQDQMLSHICLKFK-----TEGLKQQETLNNLPKAIRSSIANYLFFPIVHNIYLFQGVS 382

  Fly   663 PGCLRAFSLKFKTTHAPPGDILVHRGDVLTSLYFIARGSIEI--------QRAGNIVVLGKNDIF 719
            ...|..........:.||.:.::.:.:..|.||.:..|:::.        |..|..|:   .:.|
plant   383 RNFLFQLVSDIDAEYFPPKEDIILQNEAPTDLYILVSGAVDFTVYVDGHDQFQGKAVI---GETF 444

  Fly   720 GENPCIY----PTVGKSNGVVRALTYCDIHKLHRDDLLDVLDSYPEFLESFVSNLVITYNMRDDE 780
            ||...:|    |.      .||......|.::.|..|:..:.::.:.....::||.:  .:|..:
plant   445 GEVGVLYYRPQPF------TVRTTELSQILRISRTSLMSAMHAHADDGRVIMNNLFM--KLRGQQ 501

  Fly   781 HSGVD 785
            ...:|
plant   502 SIAID 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sei	NP_001286814.1	Ion_trans	360..583	CDD:278921	65/233 (28%)
		Ion_trans_2	<526..580	CDD:285168	17/53 (32%)
		CAP_ED	657..767	CDD:237999	22/121 (18%)
		Crp	666..>766	CDD:223736	20/111 (18%)
KAT1	NP_199436.1	PLN03192	26..677	CDD:215625	122/525 (23%)
		Ion_trans_2	230..301	CDD:285168	21/79 (27%)
		CAP_ED	377..490	CDD:237999	22/121 (18%)
		KHA	611..674	CDD:288667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2073
eggNOG	1	0.900	-	-		E1_KOG0498
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1888
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	1	0.900	-	-		OOG6_100845
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.760