DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sei and KAT2

DIOPT Version :9

Sequence 1:	NP_001286814.1	Gene:	sei / 37843	FlyBaseID:	FBgn0003353	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001329801.1	Gene:	KAT2 / 827555	AraportID:	AT4G18290	Length:	708	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	132/569 - (23%)
Similarity:	234/569 - (41%)	Gaps:	108/569 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 DMITSLGGNILLDQKLQNNYYHKWTLLHYSPFKAVWDWIILILVMYTAIFTPYVAAFLLGEQDYQ 352
            |::.|||..|....||:     |..:..:.|....|:..::|||:|:|...|:..||:    .|:
plant    43 DLLPSLGARINQSTKLR-----KHIISPFDPRFRGWEMWLVILVIYSAWICPFEFAFI----TYK 98

  Fly   353 RRNSKYINSDPIVIIDLIVDVTFIVDIIINFRTTFVNSQDE-VVSHPGRIAVHYLSGWFLIDLVA 416
            :        |.:.|||.||:..|.:|||:.|...:::|... :|..|.:||:.|||.||..|:.:
plant    99 K--------DALFIIDNIVNGFFAIDIILTFFVAYLDSHSYLLVDKPKKIAIRYLSTWFAFDVCS 155

  Fly   417 AVPFDLLLV-----GSDTDETTTLIG--LLKTARLLRLVRVA------RKIDRYSEYGAAVLILL 468
            ..||..|.:     ||:       ||  :|...||.||.||:      .|..|::.:......|:
plant   156 TAPFQSLSLLFKYNGSE-------IGFRVLSMLRLWRLRRVSSLFARLEKDIRFNYFWTRCTKLI 213

  Fly   469 MATFILIAHWLACIWYAIGNAEKSIASKNIGWLNSLAYDIQEPYFDNRTGGPSIKSRYITALYFT 533
            ..|...: |...|..|.|.:........   |:.::..:.:|         .|:.|||:||||::
plant   214 SVTLFAV-HCAGCFAYLIADQYHDPTKT---WIGAVYPNFKE---------TSVWSRYVTALYWS 265

  Fly   534 FTSLTSVGFGNVAPNTDAEKAFTICVMLVGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREF 598
            .|:||:.|:|::......|..|.:..||......:.:.||::.::....|.|..:...:....||
plant   266 ITTLTTTGYGDLHAENPREMLFFVFFMLFNLGFTSYLIGNMTNLVVHWTSRTRNFRDTVRAASEF 330

  Fly   599 IRFHQIPNPLRQRLEEY----FQHAWTYTNGIDMNSLLKGFPECLQADICLHLNRKLLTTCAAFS 659
            ...:|:|..::.::..:    |:     |.|:.....|.|.|:.:::.|..:|...::.....|.
plant   331 ASRNQLPPNIQDQMLSHICLKFK-----TEGLKQQEALNGLPKAIRSSIANYLFFPIVQNVYLFH 390

  Fly   660 EASPGCLRAFSLKFKTTHAPPGDILVHRGDVLTSLYFIARGSI--------EIQRAGNIVVLGKN 716
            ..|...|..........:.||.:.::.:.:..|.||.:..|::        |.|..|..||   .
plant   391 GVSRNFLFQLVSDIDAEYFPPREDVILQNEAPTDLYILVSGAVDFTVYVGEEDQVQGKAVV---G 452

  Fly   717 DIFGENP--CIYPTVGKSNGVVRALTYCDIHKLHRDDLLDVLDSYPEFLESFVSNLVITYNMRDD 779
            |.|||..  |..|    ....||......|.::.:..|:..:.::.|.....::||.:  .:|..
plant   453 DAFGEIGVLCYTP----QPFTVRTTELSQILRISKKSLMSAMRAHVEDGRVIMNNLFM--KLRGQ 511

  Fly   780 EHSGVD---------IK--------------------HRYLRAKSSDKM 799
            :...:|         :|                    |:||:...|:.:
plant   512 QSIAIDDPNSEPESLLKEWLVGGSKTGEGNASDQGHGHKYLQLHDSENI 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sei	NP_001286814.1	Ion_trans	360..583	CDD:278921	65/236 (28%)
		Ion_trans_2	<526..580	CDD:285168	16/53 (30%)
		CAP_ED	657..767	CDD:237999	25/119 (21%)
		Crp	666..>766	CDD:223736	23/109 (21%)
KAT2	NP_001329801.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2073
eggNOG	1	0.900	-	-		E1_KOG0498
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1888
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	1	0.900	-	-		OOG6_100845
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.760