DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sei and SKOR

DIOPT Version :9

Sequence 1:	NP_001286814.1	Gene:	sei / 37843	FlyBaseID:	FBgn0003353	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_186934.1	Gene:	SKOR / 821052	AraportID:	AT3G02850	Length:	828	Species:	Arabidopsis thaliana

Alignment Length:	496	Identity:	109/496 - (21%)
Similarity:	220/496 - (44%)	Gaps:	56/496 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 NNYYHKWTLLHYSPFKAVWDWIILILVMYTAIFTPYVAAFLLGEQDYQRRNSKYINSDPIVIIDL 369
            |.:|..||:            .|||..:|::.|||....|..|            ..:.:.|:|:
plant    79 NRWYKAWTM------------FILIWALYSSFFTPLEFGFFRG------------LPENLFILDI 119

  Fly   370 IVDVTFIVDIIINFRTTFVNSQD-EVVSHPGRIAVHYLSGWFLIDLVAAVPFDLLLVGSDTDETT 433
            ...:.|:|||::.|...:.:|:. .::.....||:.||...|:|||:|.:|:|::...:...|..
plant   120 AGQIAFLVDIVLTFFVAYRDSRTYRMIYKRSSIALRYLKSTFIIDLLACMPWDIIYKAAGEKEEV 184

  Fly   434 TLIGLLKTARLLRLVRVARKIDR--YSEYGAAVLILLMATFILIAHWLACIWYAIGNAEKSIASK 496
            ..:.|::..|:.|::....|:::  ...|....::.|:...:...|..|||:|.:.....: :.:
plant   185 RYLLLIRLYRVHRVILFFHKMEKDIRINYLFTRIVKLIFVELYCTHTAACIFYYLATTLPA-SQE 248

  Fly   497 NIGWLNSLAYDIQEPYFDNRTGGPSIKSRYITALYFTFTSLTSVGFGNVAPNTDAEKAFTICVML 561
            ...|:.||...   .|..::.....:.:||.|::||...::.:||:|::......|..|.:..:.
plant   249 GYTWIGSLKLG---DYSYSKFREIDLWTRYTTSMYFAVVTMATVGYGDIHAVNMREMIFAMVYIS 310

  Fly   562 VGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEY--FQHAWTYTN 624
            ...::.|.:.||::|:|.: .|.|.|:..:|..:..::..:::...:|.::..:  .|:..:||.
plant   311 FDMILGAYLIGNMTALIVK-GSKTERFRDKMADIMRYMNRNKLGRNIRGQITGHLRLQYESSYTE 374

  Fly   625 GIDMNSLLKGFPECLQADICLHLNRKLLTTCAAFSEASPGCLRAFSLKFKTTHAPPGDILVHRGD 689
            .    ::|:..|..::|.|...|....:.....|...|...:....::.......||::::.:|.
plant   375 A----AVLQDIPVSIRAKIAQTLYLPYIEKVPLFRGCSSEFINQIVIRLHEEFFLPGEVIMEQGS 435

  Fly   690 VLTSLYFIARGSIE---IQRAGN---IVVLGKNDIFGENP--CIYPTVGKSNGVVRALTYCDIHK 746
            |:..|||:..|.:|   |.:.|:   :.||..:..|||..  |..|    ....||....|.|.:
plant   436 VVDQLYFVCHGVLEEIGITKDGSEEIVAVLQPDHSFGEISILCNIP----QPYTVRVAELCRILR 496

  Fly   747 LHRDDLLDVLDSYPEFLESFVSNLVITYNMRDDEHSGVDIK 787
            |.:...:::|:.:      |.....|..|:.:.:.|.|.||
plant   497 LDKQSFMNILEIF------FHDGRRILNNLLEGKESNVRIK 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sei	NP_001286814.1	Ion_trans	360..583	CDD:278921	50/225 (22%)
		Ion_trans_2	<526..580	CDD:285168	14/53 (26%)
		CAP_ED	657..767	CDD:237999	26/117 (22%)
		Crp	666..>766	CDD:223736	24/107 (22%)
SKOR	NP_186934.1	PLN03192	70..827	CDD:215625	109/496 (22%)
		ANK repeat	580..611	CDD:293786
		ANK repeat	613..644	CDD:293786
		ANK repeat	677..708	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2073
eggNOG	1	0.900	-	-		E1_KOG0498
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1888
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860