Protein Alignment sei and cnga2a

DIOPT Version :10

• Sequence 1: NP_476713.1
• Gene: sei / 37843
• FlyBaseID: FBgn0003353
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001038211.1
• Gene: cnga2a / 751786
• ZFINID: ZDB-GENE-061005-1
• Length: 673
• Species: Danio rerio
• Alignment Length: 569
• Identity: 147/569 - (25%)
• Similarity: 253/569 - (44%)
• Gaps: 85/569 - (14%)

  Fly   323 WDWIILILVMYTAIFTPYVAAFLLGEQDYQRRNSKYINSDPIVIIDLIVDVTFIVDIIINFRTTF 387
            |.::|...|:|...|....|.|    .:.|.||  :|   ..:.:|.:.||.:|:|..:..||.|
Zfish   147 WLFVIASAVLYNWCFVVARACF----NELQTRN--FI---LWLFLDYLSDVIYILDTCVRLRTGF 202

  Fly   388 VNSQDEVVSHPGRIAVHYL-SGWFLIDLVAAVPFDL--LLVGSDTDETTTLIGLLKTARLLRLVR 449
            : .|..:|....::...|. :..|.:||::.:|.||  :::|....|       |:..||:|..|
Zfish   203 L-EQGLLVKDLIKLRESYFHTLQFKLDLLSIIPTDLGYIVIGIHVPE-------LRLNRLMRFSR 259

  Fly   450 VARKIDR---YSEYGAAVLILLMATFIL-IAHWLACIWYAIGNAEKSIASKNIG-----WLNSLA 505
            :....||   .:.|.....|..:..:|| |.||.|||::||        ||::|     |:..
Zfish   260 LFEFFDRTETRTSYPNLFRICNLVLYILVIIHWNACIYFAI--------SKSLGFGSDQWVYP-- 314

  Fly   506 YDIQEPYFDNRTGGPSIKSRYITALYFTFTSLTSVGFGNVAPNTDAEKAFTICVMLVGSLMYASI 570
             :|.:|.|...|.|      |:..||::..:||::| ...||..|.|..|.:...|||.|::|:|
Zfish   315 -NISDPKFGTLTRG------YVYCLYWSTLTLTTIG-EMPAPVQDEEYLFVVFDFLVGVLIFATI 371

  Fly   571 FGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNSLLKGF 635
            .|||.|:|..:.:..|.:..|:..::.:::|.::...|..|:.::|.:.||....||...:||..
Zfish   372 VGNVGAMISNMNATRAEFQGQIDAIKHYMKFRKVSKELEARVIKWFDYLWTNKKTIDEQDVLKNL 436

  Fly   636 PECLQADICLHLNRKLLTTCAAFSEASPGCLRAFSLKFKTTHAPPGDILVHRGDVLTSLYFIARG 700
            |..|:|:|.::::.:.|.....|.:...|.|....||.:.....|||.:..:||:...:|.|..|
Zfish   437 PNKLRAEIAINVHLETLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEG 501

  Fly   701 SIEIQRAGNIVV---LGKNDIFGENPCIYPTVGKSNG-----VVRALTYCDIHKLHRDDLLDVLD 757
            .:.:.....:..   |.....||| ..|....|...|     .:|::.|.|:..|.:.||::.:.
Zfish   502 CLAVVADDGVTQYAHLTAGSCFGE-ISILNIRGSKMGNRRTANIRSIGYSDLFCLSKGDLMEAVM 565

  Fly   758 SYPE---FLESFVSNLVITYNMRDD-EHSGV---DIKHRYLRAKSSDKMRSSPDIPSIRIVGL-- 813
            .||:   .||.....::|...:.:: |..|:   ||:.|.      ::|..:.:|...|...|
Zfish   566 EYPDAKKVLEEKGRQILIKEGLLEEVEADGIGVEDIEKRV------ERMEDTIEILQTRFARLLA 624

  Fly   814 ------RYKKQNVNTSVHKVKNDNSRDLNIFIENEI--------ANYHL 848
                  ::.||.:.|...:..:..|..|:...|:.|        .|.||
Zfish   625 QYTATQQHLKQRLTTLECRTNHSGSGFLSDGNESTIDGDGTNSEVNIHL 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sei	NP_476713.1	Ion_trans	322..583	CDD:459842	80/271 (30%)
		CAP_ED	657..767	CDD:237999	30/120 (25%)
cnga2a	NP_001038211.1	Ion_trans	144..386	CDD:459842	80/273 (29%)
		CAP_ED	458..574	CDD:237999	28/116 (24%)
		CLZ	574..642	CDD:465160	15/73 (21%)