DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sei and hcn5

DIOPT Version :9

Sequence 1:	NP_001286814.1	Gene:	sei / 37843	FlyBaseID:	FBgn0003353	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	XP_017213269.1	Gene:	hcn5 / 101884258	ZFINID:	ZDB-GENE-081105-169	Length:	305	Species:	Danio rerio

Alignment Length:	276	Identity:	62/276 - (22%)
Similarity:	109/276 - (39%)	Gaps:	66/276 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 LLHYSPFKAVWDWIILILVMYT---AIFTPYVAAFLLGEQDYQRRNSKYINSDPIVIIDLIVDVT 374
            ::|  ||..:..:.|:.:|..|   .|..|...|||.|........           .::..|..
Zfish    53 VIH--PFSRLRSYYIMCMVAITFLNLIGIPMEIAFLDGNSGVGWEG-----------FNVFSDTL 104

  Fly   375 FIVDIIINFRTTFVNSQ-DEVVSHPGRIAVHYLSGWFLIDLVAAVPFDLLLVGSD----TDETTT 434
            |::|:.:|||...:... :..:.....|...||..||:.|||||.|...:|:.:|    :|..::
Zfish   105 FLIDVGVNFRMGIIPEDCERAILDLKSIRHRYLKSWFIPDLVAAFPVGYILLIADLQYHSDSPSS 169

  Fly   435 -------------LIGLLKTARLLRLVRVARKIDRYSEYGAAV-------LILLMATFILIAHWL 479
                         :|.|::..|:.||||...:::|.|.....|       |.|.|..| |:.||.
Zfish   170 KASKMMRILMFVRIISLVRLLRVSRLVRFFNEVERVSNANLEVVRVFLKILSLFMMIF-LLCHWN 233

  Fly   480 ACIWYAIGNAEKS-----IASKNIGWLNSLAYDIQEPYFDNRTGGPSIKSRYITALYFTFTSLTS 539
            .||.|.:...|:.     :..:|:  :|:                 |:..:|...::...:.:|:
Zfish   234 GCIQYFVPMLEEFPSDCWVRRENL--MNA-----------------SVGEKYSFGVFRALSHMTA 279

  Fly   540 VGFGNVAPNTDAEKAF 555
            :.:|:....|..|..|
Zfish   280 ISYGSSETPTSKEYTF 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sei	NP_001286814.1	Ion_trans	360..583	CDD:278921	50/226 (22%)
		Ion_trans_2	<526..580	CDD:285168	6/30 (20%)
		CAP_ED	657..767	CDD:237999
		Crp	666..>766	CDD:223736
hcn5	XP_017213269.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910