DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaSnap1 and SEC17

DIOPT Version :9

Sequence 1:	NP_477469.1	Gene:	gammaSnap1 / 37842	FlyBaseID:	FBgn0028552	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_009503.1	Gene:	SEC17 / 852230	SGDID:	S000000146	Length:	292	Species:	Saccharomyces cerevisiae

Alignment Length:	299	Identity:	67/299 - (22%)
Similarity:	125/299 - (41%)	Gaps:	35/299 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IAEAEDLVKQAEKSLKLSMLKWVPD--------------YDSAADEYSKAATAYRIAKSYDKSKE 59
            :::..:|:|:|||       |.||.              ::.|||...:|||.||:.|..:.:.:
Yeast     1 MSDPVELLKRAEK-------KGVPSSGFMKLFSGSDSYKFEEAADLCVQAATIYRLRKELNLAGD 58

  Fly    60 CFLKAIDAYKNNKSWFHAAKAY-EQIILLSKDADKLHEVEEYANKSASLYQQHGSPEAAASALDK 123
            .||||.|..|...:...|...| |.........:.::.|:...| :..::...|.....|:...:
Yeast    59 SFLKAADYQKKAGNEDEAGNTYVEAYKCFKSGGNSVNAVDSLEN-AIQIFTHRGQFRRGANFKFE 122

  Fly   124 AAKLTESKHPD--MALRFYQHALEVIMIEDSVRQAAEYASKVSRILVKLRRYDEATNALKKEISL 186
            ..::.|:...|  .|:..|:.|.|....:.||..:.:...|.:.:.....:|.||::...|.|..
Yeast   123 LGEILENDLHDYAKAIDCYELAGEWYAQDQSVALSNKCFIKCADLKALDGQYIEASDIYSKLIKS 187

  Fly   187 NQQTE-SYGQIGRLVVALVMVQLARGDSVEAEKTFREW----GNCCEPEEVSTLQTLLQAFDDED 246
            :.... |...:....:...:.|||..|:|.|.:|.:|.    .|..:..|.:.|::|:.|.::.|
Yeast   188 SMGNRLSQWSLKDYFLKKGLCQLAATDAVAAARTLQEGQSEDPNFADSRESNFLKSLIDAVNEGD 252

  Fly   247 PELAARMLA--SPFIRHMDVEYAILSKNIPLPQGIQMEK 283
            .|..:....  ..|:|....:..||:|   :.:.||.::
Yeast   253 SEQLSEHCKEFDNFMRLDKWKITILNK---IKESIQQQE 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaSnap1	NP_477469.1	SNAP	11..248	CDD:305195	59/258 (23%)
		TPR repeat	33..70	CDD:276937	14/50 (28%)
		TPR repeat	74..111	CDD:276937	5/37 (14%)
		TPR repeat	114..149	CDD:276937	7/36 (19%)
		TPR repeat	153..187	CDD:276937	7/33 (21%)
SEC17	NP_009503.1	SNAP	10..284	CDD:405606	63/284 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346316
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840