DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaSnap1 and Y59A8B.8

DIOPT Version :9

Sequence 1:	NP_477469.1	Gene:	gammaSnap1 / 37842	FlyBaseID:	FBgn0028552	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_507527.2	Gene:	Y59A8B.8 / 180182	WormBaseID:	WBGene00013345	Length:	299	Species:	Caenorhabditis elegans

Alignment Length:	309	Identity:	95/309 - (30%)
Similarity:	160/309 - (51%)	Gaps:	17/309 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGIAAKKIAEAEDLVKQAEKSLKLSM--LKWVPDYDSAADEYSKAATAYRIAKSYDKSKECFLK 63
            ||..|  ::.||.:..::||..:|.||  ||:.||:|.||....:|:..||.|:...|:....||
Worm     1 MSNTA--RLKEAAECERKAEDCMKTSMIKLKFKPDFDGAASAMERASVCYRNAQDPKKAAGSLLK 63

  Fly    64 AIDAYKNNKSWFHAAKAYEQIILLSKDADKLHEVEEYANKSASLYQQHGSPEAAASALDKAAKLT 128
            |.:.|:.|::.||||||.|...:|.:|..:..|......|:.:.|.:.||.:.||..::|||.:.
Worm    64 AAEYYEQNRNLFHAAKAREGAAMLLRDIKEFSEAVVLFEKAINGYAESGSLDTAAMTVEKAADVL 128

  Fly   129 ESKHPDMALRFYQHALEVIMIEDSVRQAAEYASKVSRILVKLRRYDEATNALKKEISLNQQTESY 193
            ::.:|..||:.||..|.::...|..:.|:.:..:::::.::|..|..|..::::||....:...|
Worm   129 KNDNPKEALQIYQRGLALVQQSDRAKMASNFLKQITKLSLQLTDYKGALGSIREEIEKFAEIREY 193

  Fly   194 GQIGRLVVALVMVQLARGDSVEAEKTFREWGNCCEP-----EEVSTLQTLLQAFDDEDPELAARM 253
            .:||:|.:.||:|.||..|||.|.|.: .|..|..|     |:....:.|:..::..|.|....:
Worm   194 PRIGQLGIGLVIVNLALEDSVAALKDY-GWVICQSPDFQTSEDGRVCENLIGFYEAGDDESFQNV 257

  Fly   254 LASPFIRHMDVEYAILSKNIPLPQGIQMEKKAGDTAAETNDAEDEGGLC 302
            |....:|.||.||..:.|.:..|.|     .||  ..:..:.:|:.|||
Worm   258 LKCGALRSMDNEYLRVMKILKAPSG-----NAG--LGDGQEDDDDEGLC 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaSnap1	NP_477469.1	SNAP	11..248	CDD:305195	76/243 (31%)
		TPR repeat	33..70	CDD:276937	13/36 (36%)
		TPR repeat	74..111	CDD:276937	12/36 (33%)
		TPR repeat	114..149	CDD:276937	11/34 (32%)
		TPR repeat	153..187	CDD:276937	6/33 (18%)
Y59A8B.8	NP_507527.2	SNAP	9..276	CDD:305195	83/267 (31%)
		TPR repeat	33..70	CDD:276937	13/36 (36%)
		TPR_12	37..108	CDD:290160	23/70 (33%)
		TPR repeat	74..111	CDD:276937	12/36 (33%)
		TPR repeat	114..149	CDD:276937	11/34 (32%)
		TPR repeat	153..189	CDD:276937	6/35 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166913
Domainoid	1	1.000	124	1.000	Domainoid score	I3413
eggNOG	1	0.900	-	-		E1_KOG1585
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2838
Inparanoid	1	1.050	142	1.000	Inparanoid score	I3057
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55184
OrthoDB	1	1.010	-	-		D1540214at2759
OrthoFinder	1	1.000	-	-		FOG0003744
OrthoInspector	1	1.000	-	-		mtm4851
orthoMCL	1	0.900	-	-		OOG6_103437
Panther	1	1.100	-	-	LDO	PTHR13768
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4330
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.840