| Sequence 1: | NP_001286812.1 | Gene: | MAN1 / 37838 | FlyBaseID: | FBgn0034962 | Length: | 650 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055134.2 | Gene: | LEMD3 / 23592 | HGNCID: | 28887 | Length: | 911 | Species: | Homo sapiens |
| Alignment Length: | 631 | Identity: | 158/631 - (25%) |
|---|---|---|---|
| Similarity: | 263/631 - (41%) | Gaps: | 126/631 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 85 ANGLDNNNDLDQTGGSSAYNRSLDESDSSPL---QLSASKM--YAPPPVVASNYDGDCSPHSLGL 144
Fly 145 NGKYLQPCSMPYAIDTSNNYGK---PSGKAKLSDGGVVNRL--LSFRDTTIQRKFNYPTGQASRI 204
Fly 205 PLRKERLTRFALSDLKSFIRNPDIRP------YVIPRVLISLFLIFLTIITVLYVGKRFEQSPID 263
Fly 264 KAALKYTLCNPNDMQMISEKVNCIEKDSLRGALDMSEELFRHLNERARLHHCKDANLSPALEIGE 328
Fly 329 FVREMVSNPKTHRGNLHSNLMAAKYLITENPQW------SIQ-VVDSTKHLG------------- 373
Fly 374 QTSHFELSEPNLPLKCIVLKKVTRFFTVIGALLLIVAGFLIVYVAVVI----YR-VKQKEALLAV 433
Fly 434 DQFQKDIINELIYLSSQSES--------PEVVINQLQEKFLPAKKRSKLLSSWNKALKQLEKNDS 490
Fly 491 RVLFGMVNRDGKA----MRTIAWNRNVDKKDVGLVKKWQSPAF--DNSNKIANPPTPCLKIRHMF 549
Fly 550 DS-SEV-DQANLKQSIVESIIEKVGTRCKICDVQLDVQS--CCVYIRCASEEDAGTIHKEINGWW 610
Fly 611 FDKRLISIKFLRLERYLSRFP---------KPSAEPLYFHTNEAAN 647 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MAN1 | NP_001286812.1 | LEM | 4..47 | CDD:128813 | |
| MSC | <381..509 | CDD:286487 | 37/144 (26%) | ||
| RRM_Man1 | 542..631 | CDD:240732 | 41/92 (45%) | ||
| LEMD3 | NP_055134.2 | LEM | 9..51 | CDD:383069 | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 19..38 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 43..89 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 111..130 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 140..354 | 8/29 (28%) | |||
| MSC | <538..748 | CDD:370465 | 51/237 (22%) | ||
| Interaction with SMAD1, SMAD2, SMAD3 and SMAD5. /evidence=ECO:0000269|PubMed:15647271 | 699..911 | 75/206 (36%) | |||
| RRM_Man1 | 785..876 | CDD:240732 | 41/92 (45%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 879..911 | 5/23 (22%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141032 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0147 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 151 | 1.000 | Inparanoid score | I4372 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D593495at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0004711 | |
| OrthoInspector | 1 | 1.000 | - | - | oto88738 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_106535 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR13428 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2606 |
| SonicParanoid | 1 | 1.000 | - | - | X5852 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.790 | |||||