DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chi and MFG1

DIOPT Version :9

Sequence 1:	NP_726403.2	Gene:	Chi / 37837	FlyBaseID:	FBgn0013764	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_010048.1	Gene:	MFG1 / 851365	SGDID:	S000002392	Length:	458	Species:	Saccharomyces cerevisiae

Alignment Length:	504	Identity:	105/504 - (20%)
Similarity:	161/504 - (31%)	Gaps:	175/504 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 GNPYPPAGQSSPAGNQSIVFQNSNQPGSNTPQYTSSPAPSGSSTPGPVGAQNIPGN-YPQSATAG 144
            |.|.||. |:.|   ...:..|      |||.|     |:|:....|...||||.. |||...
Yeast     4 GPPQPPP-QAVP---MPYIVNN------NTPPY-----PNGNINFPPTAQQNIPPTVYPQQVP-- 51

  Fly   145 NFNG-PVGGPFGSPSSGLGQFSR-PASSGTPFNSGQ-------AGHFSSPTVFSVGGQFNPM--- 197
             |.| |.||.|..|||....|:: |..:.|..||.|       .|..|.|....|....:||
Yeast    52 -FPGQPQGGQFPQPSSEQQVFNQLPQVTQTFHNSAQNTNATGGPGSGSMPMFTPVASFPHPMATA 115

  Fly   198 -PPASPFGHGGNHPMMGGPQQMERIDQGFRRHNSYFSHTEHRVFELNKRLQQRNEESDNCWWDSF 261
             ..|:|.....:...:    .|.|:....|::.|..:     :.:|.:.:.:.|.........||
Yeast   116 ATAAAPLPRSASQASL----SMLRVPYHVRKYLSNLA-----MLKLYEIINEVNTAMGKIGLLSF 171

  Fly   262 TTEFFEDDARLTILFCLEDGPKRY-----------------------TIGRTLIPRFFRSIYEGG 303
            .||...|      :| ..|...||                       |:||..|.|....:
Yeast   172 WTELISD------IF-TPDAVIRYSKKSMTDYREFEFIIPVFPVICSTLGRFGIVRMEVKV---- 225

  Fly   304 VSDLYFQLKHAKESFHNTSITLDCDQCTVITQHGKPFFTKVCADARLILEF-----MYDDYMRIK 363
                 .|||  .:...|::|..:|.:.|         |.....|...|..|     .:|..::|
Yeast   226 -----LQLK--TQVLSNSTIFFNCPRVT---------FVYYYPDGSYITHFSQMKGAFDLDLKI- 273

  Fly   364 SWHMTIKGH----------------------------RELIPRSV----------IGTSLPPDPM 390
            :| :.:..|                            |:|....|          ..|::||:..
Yeast   274 NW-LDVSMHSFVPDIEWNAVERLLSDDTKSTEIEQIFRKLKQEDVKEQGNSFAENNATNVPPNFE 337

  Fly   391 LLDQ------ITKNITRAGITNSTLNYLRLCVILEPMQELMSRHKAYALSPRDCLKTTLFQKWQR 449
            .:.|      :.:|::..|.....:..:::..::..::.|..                 ||..:.
Yeast   338 AITQLRSYFDVFRNVSVFGTQEGLMRVMQISTVMSTLKNLRK-----------------FQIEKN 385

  Fly   450 MVAP---------PGKKDPQRPP--NKRRKRKG-----SNSGGGNNSNT 482
            :.:|         ..|||....|  .|||:..|     :..|...||||
Yeast   386 IDSPVTALSAYIDADKKDSGSEPLHAKRRRNSGISPRTTTLGPNGNSNT 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chi	NP_726403.2	LIM_bind	238..440	CDD:280051	41/273 (15%)
MFG1	NP_010048.1	Atrophin-1	<24..>137	CDD:397323	37/124 (30%)
MFG1	NP_010048.1	LIM_bind	151..393	CDD:396393	44/287 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10378
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100