DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chi and ldb1

DIOPT Version :9

Sequence 1:	NP_726403.2	Gene:	Chi / 37837	FlyBaseID:	FBgn0013764	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	XP_031760822.1	Gene:	ldb1 / 407886	XenbaseID:	XB-GENE-493239	Length:	411	Species:	Xenopus tropicalis

Alignment Length:	398	Identity:	243/398 - (61%)
Similarity:	292/398 - (73%)	Gaps:	23/398 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 PFNSGQAGHFSSPTVFSVGGQFNPMPPASPFGHGGNHPMMGGPQQMERIDQGFRRHNSYFSHTEH 237
            |..|.::....||.....|..|.|..|.:..........|..|..:|   .|..||..|.:.|::
Frog     8 PGCSSKSFKLYSPKEPPNGNAFPPFHPGTMLDRDVGPTPMYPPTYLE---PGIGRHTPYGNQTDY 69

  Fly   238 RVFELNKRLQQRNEESDNCWWDSFTTEFFEDDARLTILFCLEDGPKRYTIGRTLIPRFFRSIYEG 302
            |:||||||||...||.||.|||:||||||||||.|||.|||||||||||||||||||:||||:||
Frog    70 RIFELNKRLQNWTEECDNLWWDAFTTEFFEDDAMLTITFCLEDGPKRYTIGRTLIPRYFRSIFEG 134

  Fly   303 GVSDLYFQLKHAKESFHNTSITLDCDQCTVITQHGKPFFTKVCADARLILEFMYDDYMRIKSWHM 367
            |.::||:.|||.||||||..::|||||||::||||||.||:||.:.||.||||:||.||||:||.
Frog   135 GATELYYVLKHPKESFHNNFVSLDCDQCTMVTQHGKPMFTQVCVEGRLYLEFMFDDMMRIKTWHF 199

  Fly   368 TIKGHRELIPRSVIGTSLPPDPMLLDQITKNITRAGITNSTLNYLRLCVILEPMQELMSRHKAYA 432
            :|:.||||||||::... ..||.:|||::|||||.|::||||||||||||||||||||||||.|:
Frog   200 SIRQHRELIPRSILAMH-AQDPQMLDQLSKNITRCGLSNSTLNYLRLCVILEPMQELMSRHKTYS 263

  Fly   433 LSPRDCLKTTLFQKWQRMVAPPGKKDPQR-PPNKRRKRKGS-----NSGGGNNSNTPPVTNQKRS 491
            |||||||||.||||||||||||.  :|.| .||||||||.|     :|||||.:|:   .::|:|
Frog   264 LSPRDCLKTCLFQKWQRMVAPPA--EPARQAPNKRRKRKMSGGSTMSSGGGNTNNS---NSKKKS 323

  Fly   492 PSGPSFSLSSQ--DVMVVGEPTLMGGEFGEEDERLITRLENTQYDGTNAVEHDNHTGFGHADSPI 554
            |:. :|:||||  ||||||||||||||||:|||||||||||||:|..|.:  |:...|.  :||.
Frog   324 PAS-TFALSSQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQFDAANGI--DDEDSFN--NSPA 383

  Fly   555 SGSN-PWS 561
            .|:| ||:
Frog   384 LGANSPWN 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chi	NP_726403.2	LIM_bind	238..440	CDD:280051	148/201 (74%)
ldb1	XP_031760822.1	LIM_bind	70..271	CDD:396393	148/201 (74%)
ldb1	XP_031760822.1	LID	336..364	CDD:407766	26/27 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	243	1.000	Domainoid score	I2168
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	469	1.000	Inparanoid score	I1486
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002757
OrthoInspector	1	1.000	-	-		otm49262
Panther	1	1.100	-	-	O	PTHR10378
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3240
SonicParanoid	1	1.000	-	-		X1842
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.090