DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Chi and ldb1a

DIOPT Version :9

Sequence 1:	NP_726403.2	Gene:	Chi / 37837	FlyBaseID:	FBgn0013764	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	XP_005156813.1	Gene:	ldb1a / 30579	ZFINID:	ZDB-GENE-990415-138	Length:	418	Species:	Danio rerio

Alignment Length:	427	Identity:	245/427 - (57%)
Similarity:	298/427 - (69%)	Gaps:	38/427 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 PFNSGQAGHFSSPTVFSVGGQFNPMPPASPFGHGGNHPMMGGPQQMERIDQGFRRHNSYFSHTEH 237
            |..|.::....||.....|..|.|..|.:..........|..|..||   .|..||..|.:.|::
Zfish     9 PGCSSKSFKLYSPKEPPNGSAFPPFHPGAMLDRDVGPTPMYPPSYME---PGIGRHTPYGNQTDY 70

  Fly   238 RVFELNKRLQQRNEES-DNCWWDSFTTEFFEDDARLTILFCLEDGPKRYTIGRTLIPRFFRSIYE 301
            |:||||||||...|:. ||.|||:||||||||||.|||.|||||||||||||||||||:||||:|
Zfish    71 RIFELNKRLQNWTEQDCDNLWWDAFTTEFFEDDAMLTITFCLEDGPKRYTIGRTLIPRYFRSIFE 135

  Fly   302 GGVSDLYFQLKHAKESFHNTSITLDCDQCTVITQHGKPFFTKVCADARLILEFMYDDYMRIKSWH 366
            ||.::|::.|||.||||||..::|||||||::||:|||.||:||.:.||.||||:||.||||:||
Zfish   136 GGATELFYVLKHPKESFHNNFVSLDCDQCTMVTQNGKPMFTQVCVEGRLYLEFMFDDMMRIKTWH 200

  Fly   367 MTIKGHRELIPRSVIG----TSLPPDPMLLDQITKNITRAGITNSTLNYLRLCVILEPMQELMSR 427
            .:|:.|||::|||::.    :....||.:|||::|||||.|::||||||||||||||||||||||
Zfish   201 FSIRQHREVVPRSILAMHPFSQQAQDPQMLDQLSKNITRCGLSNSTLNYLRLCVILEPMQELMSR 265

  Fly   428 HKAYALSPRDCLKTTLFQKWQRMVAPPGKKDPQR-PPNKRRKRKGS-----NSGGGNNSNTPPVT 486
            ||.|:|||||||||.||||||||||||.  :|.| .||||||||.|     :||||||:|:   .
Zfish   266 HKTYSLSPRDCLKTCLFQKWQRMVAPPA--EPARQAPNKRRKRKMSGGSTMSSGGGNNNNS---N 325

  Fly   487 NQKRSPSGPSFSLSSQ--DVMVVGEPTLMGGEFGEEDERLITRLENTQYDGTNAVEHDNHTGFGH 549
            ::|:||:. ||:||||  ||||||||||||||||:|||||||||||||:|..|.:  |:...|.
Zfish   326 SKKKSPAS-SFALSSQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQFDAANGI--DDEDSFN- 386

  Fly   550 ADSPISGSNPWSIDRAGAIPASPGNGAAPQNNANISD 586
             .||..|:|            ||.|..||.:....:|
Zfish   387 -SSPTMGTN------------SPWNSKAPSSQQGKND 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chi	NP_726403.2	LIM_bind	238..440	CDD:280051	143/206 (69%)
ldb1a	XP_005156813.1	LIM_bind	71..278	CDD:307769	143/206 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579857
Domainoid	1	1.000	238	1.000	Domainoid score	I2238
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	461	1.000	Inparanoid score	I1534
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002757
OrthoInspector	1	1.000	-	-		otm25566
orthoMCL	1	0.900	-	-		OOG6_105360
Panther	1	1.100	-	-	O	PTHR10378
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3240
SonicParanoid	1	1.000	-	-		X1842
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.920