DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chi and Ldb2

DIOPT Version :9

Sequence 1:	NP_726403.2	Gene:	Chi / 37837	FlyBaseID:	FBgn0013764	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_001099479.1	Gene:	Ldb2 / 289664	RGDID:	1307921	Length:	373	Species:	Rattus norvegicus

Alignment Length:	374	Identity:	232/374 - (62%)
Similarity:	276/374 - (73%)	Gaps:	33/374 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 PMPP--ASPFGHGGNHPMMGGPQQMERIDQGFRRHNSYFSHTEHRVFELNKRLQQRNEESDNCWW 258
            |..|  :||||     |.             :|||..|....|:|::|:|||||.|.|:|||.||
  Rat     5 PHDPFYSSPFG-----PF-------------YRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWW 51

  Fly   259 DSFTTEFFEDDARLTILFCLEDGPKRYTIGRTLIPRFFRSIYEGGVSDLYFQLKHAKESFHNTSI 323
            |:|.||||||||.||:.|||||||||||||||||||:|.:::||||:|||:.|||:|||:||:||
  Rat    52 DAFATEFFEDDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSI 116

  Fly   324 TLDCDQCTVITQHGKPFFTKVCADARLILEFMYDDYMRIKSWHMTIKGHRELIPRSVIGTSLPPD 388
            |:|||||.::||||||.|||||.:.||||||.:||.||||:||.||:.:|||:|||::... ..|
  Rat   117 TVDCDQCAMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMH-AQD 180

  Fly   389 PMLLDQITKNITRAGITNSTLNYLRLCVILEPMQELMSRHKAYALSPRDCLKTTLFQKWQRMVAP 453
            |.:|||::|||||.|:||.||||||||||||||||||||||.|.|||||||||.|||||||||||
  Rat   181 PQVLDQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQRMVAP 245

  Fly   454 PGKKDPQR-PPNKRRKRKGSNSGGGNNS--NTPPVTNQKRSPSGPSFSLSSQ--DVMVVGEPTLM 513
            |.  :|.| |..||||||.|.|...|:|  ||......|:..:..|.|||:|  |||||||||||
  Rat   246 PA--EPTRQPTTKRRKRKNSTSSTSNSSAGNTTNSAGSKKKTTAASLSLSTQVPDVMVVGEPTLM 308

  Fly   514 GGEFGEEDERLITRLENTQYDGTNAVEHDNHTGFGHADSPISGSN-PWS 561
            |||||:|||||||||||||||..|.:  |:...|.  :||..|:| ||:
  Rat   309 GGEFGDEDERLITRLENTQYDAANGM--DDEEDFN--NSPALGNNSPWN 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chi	NP_726403.2	LIM_bind	238..440	CDD:280051	144/201 (72%)
Ldb2	NP_001099479.1	LIM_bind	31..232	CDD:396393	144/201 (72%)
Ldb2	NP_001099479.1	LID	298..326	CDD:407766	26/27 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340039
Domainoid	1	1.000	241	1.000	Domainoid score	I2171
eggNOG	1	0.900	-	-		E1_KOG2181
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H989
Inparanoid	1	1.050	461	1.000	Inparanoid score	I1497
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002757
OrthoInspector	1	1.000	-	-		otm46178
orthoMCL	1	0.900	-	-		OOG6_105360
Panther	1	1.100	-	-	LDO	PTHR10378
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1842
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.750